Localized Translation of gurken/TGF-α mRNA during Axis Specification Is Controlled by Access to Orb/CPEB on Processing Bodies

In Drosophila oocytes, gurken/TGF-α mRNA is essential for establishing the future embryonic axes. gurken remains translationally silent during transport from its point of synthesis in nurse cells to its final destination in the oocyte, where it associates with the edge of processing bodies. Here we...

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Bibliografiske detaljer
Main Authors: Alexander Davidson, Richard M. Parton, Catherine Rabouille, Timothy T. Weil, Ilan Davis
Format: Article
Sprog:English
Udgivet: Elsevier 2016-03-01
Serier:Cell Reports
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124716301413