The Relevance of Thiamine Evaluation in a Practical Setting
Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in thiamine, and it can be denatured by high temperature...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/9/2810 |
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| author | Federico Pacei Antonella Tesone Nazzareno Laudi Emanuele Laudi Anna Cretti Shira Pnini Fabio Varesco Chiara Colombo |
| author_facet | Federico Pacei Antonella Tesone Nazzareno Laudi Emanuele Laudi Anna Cretti Shira Pnini Fabio Varesco Chiara Colombo |
| author_sort | Federico Pacei |
| collection | DOAJ |
| description | Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in thiamine, and it can be denatured by high temperature and pH. Additionally, different drugs can alter thiamine metabolism. In addition, the half-life of thiamine in the body is between 1 and 3 weeks. All these factors could provide an explanation for the relatively short period needed to develop thiamine deficiency and observe the consequent clinical symptoms. Thiamine deficiency could lead to neurological and cardiological problems. These clinical conditions could be severe or even fatal. Marginal deficiency too may promote weaker symptoms that might be overlooked. Patients undergoing upper gastrointestinal or pancreatic surgery could have or develop thiamine deficiency for many different reasons. To achieve the best outcome for these patients, we strongly recommend the execution of both an adequate preoperative nutritional assessment, which includes thiamine evaluation, and a close nutritional follow up to avoid a nutrient deficit in the postoperative period. |
| first_indexed | 2024-03-10T16:22:00Z |
| format | Article |
| id | doaj.art-e1616b8e9cc54bb4bf54d724e0583ee8 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T16:22:00Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-e1616b8e9cc54bb4bf54d724e0583ee82023-11-20T13:36:56ZengMDPI AGNutrients2072-66432020-09-01129281010.3390/nu12092810The Relevance of Thiamine Evaluation in a Practical SettingFederico Pacei0Antonella Tesone1Nazzareno Laudi2Emanuele Laudi3Anna Cretti4Shira Pnini5Fabio Varesco6Chiara Colombo7ASST Nord Milano, UOC Neurologia, Ospedale Bassini, 20092 Cinisello Balsamo, ItalyDepartment of Physical Rehabilitation, Casa di Cura Bonvicini, Via Michael Pacher 12, 39100 Bolzano, ItalyFaculty of Medicine and Surgery, Medizinische Universitat Innsbruck, Christoph-Probst-Platz 1, Innrain 52 A, 6020 Innsbruck, AustriaDepartment of Physical Rehabilitation, Casa di Cura Bonvicini, Via Michael Pacher 12, 39100 Bolzano, ItalyDepartment of Physical Rehabilitation, Casa di Cura Bonvicini, Via Michael Pacher 12, 39100 Bolzano, ItalyDepartment of Physical Rehabilitation, Casa di Cura Bonvicini, Via Michael Pacher 12, 39100 Bolzano, ItalyDepartment of Physical Rehabilitation, Casa di Cura Bonvicini, Via Michael Pacher 12, 39100 Bolzano, ItalyLombardy Regional Course for General Practitioner, PoliS-Lombardia, Via Taramelli 12/F, 20100 Milano, ItalyThiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in thiamine, and it can be denatured by high temperature and pH. Additionally, different drugs can alter thiamine metabolism. In addition, the half-life of thiamine in the body is between 1 and 3 weeks. All these factors could provide an explanation for the relatively short period needed to develop thiamine deficiency and observe the consequent clinical symptoms. Thiamine deficiency could lead to neurological and cardiological problems. These clinical conditions could be severe or even fatal. Marginal deficiency too may promote weaker symptoms that might be overlooked. Patients undergoing upper gastrointestinal or pancreatic surgery could have or develop thiamine deficiency for many different reasons. To achieve the best outcome for these patients, we strongly recommend the execution of both an adequate preoperative nutritional assessment, which includes thiamine evaluation, and a close nutritional follow up to avoid a nutrient deficit in the postoperative period.https://www.mdpi.com/2072-6643/12/9/2810thiaminethiamine deficiencypolineuropathyWernicke’s encephalopathywet beriberimalnutrition |
| spellingShingle | Federico Pacei Antonella Tesone Nazzareno Laudi Emanuele Laudi Anna Cretti Shira Pnini Fabio Varesco Chiara Colombo The Relevance of Thiamine Evaluation in a Practical Setting Nutrients thiamine thiamine deficiency polineuropathy Wernicke’s encephalopathy wet beriberi malnutrition |
| title | The Relevance of Thiamine Evaluation in a Practical Setting |
| title_full | The Relevance of Thiamine Evaluation in a Practical Setting |
| title_fullStr | The Relevance of Thiamine Evaluation in a Practical Setting |
| title_full_unstemmed | The Relevance of Thiamine Evaluation in a Practical Setting |
| title_short | The Relevance of Thiamine Evaluation in a Practical Setting |
| title_sort | relevance of thiamine evaluation in a practical setting |
| topic | thiamine thiamine deficiency polineuropathy Wernicke’s encephalopathy wet beriberi malnutrition |
| url | https://www.mdpi.com/2072-6643/12/9/2810 |
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