Direct and indirect effects of IFN-α2b in malignancy treatment: not only an archer but also an arrow

Direct and indirect effects of IFN-α2b in malignancy treatment: not only an archer but also an arrow

Abstract Interferon-α2b (IFN-α2b) is a highly active cytokine that belongs to the interferon-α (IFN-α) family. IFN-α2b has beneficial antiviral, antitumour, antiparasitic and immunomodulatory activities. Direct and indirect antiproliferative effects of IFN-α2b have been found to occur via multiple p...

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Bibliographic Details
Main Authors: Fei Xiong, Qi Wang, Guan-hua Wu, Wen-zheng Liu, Bing Wang, Yong-jun Chen
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Biomarker Research
Subjects:
Interferon
IFN-α2b
Antitumour effects
Immune response
JAK-STAT pathway
Online Access:https://doi.org/10.1186/s40364-022-00415-y

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