Transient early preeclampsia in twin pregnancy with a triploid fetus: a case report

<p>Abstract</p> <p>Introduction</p> <p>Triploid pregnancies have an increased risk of early preeclampsia. Twin pregnancies consisting of one healthy fetus and one complete or partial molar, with or without a triploid fetus, are rare and management is complex.</p>...

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Bibliographic Details
Main Authors: van der Houwen Clasien, Schukken Tineke, van Pampus Mariëlle
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/3/1/7311
Description
Summary:<p>Abstract</p> <p>Introduction</p> <p>Triploid pregnancies have an increased risk of early preeclampsia. Twin pregnancies consisting of one healthy fetus and one complete or partial molar, with or without a triploid fetus, are rare and management is complex.</p> <p>Case presentation</p> <p>A 33-year-old Caucasian woman presented with a dichorionic diamniotic twin pregnancy. One fetus showed early growth restriction resulting in fetal death at 20 weeks. The placenta was enlarged with some cysts. Chorionic villus biopsy confirmed triploidy. At 21 weeks, the patient developed preeclampsia with a blood pressure of 154/98 mmHg and proteinuria (24 hour protein excretion of 2.5 g/L), for which she was hospitalized. Without pharmacological interventions, the blood pressure normalized and proteinuria disappeared. At 35 weeks, she again developed preeclampsia. A cesarean section was performed at 38 weeks and a healthy child was born.</p> <p>Conclusions</p> <p>Survival of the healthy fetus is possible in a twin pregnancy with a triploid fetus complicated by early preeclampsia. The pregnancy should not be terminated if the triploid twin has died and as long as conservative management is safe.</p>
ISSN:1752-1947