Dual clathrin and integrin signaling systems regulate growth factor receptor activation
The integration and organization of growth factor signaling, adhesion, and endocytosis is poorly understood. Here the authors use light and electron microscopy to shed light on the role of flat clathrin lattices and cell adhesion in growth factor signaling.
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-28373-x |
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author | Marco A. Alfonzo-Méndez Kem A. Sochacki Marie-Paule Strub Justin W. Taraska |
author_facet | Marco A. Alfonzo-Méndez Kem A. Sochacki Marie-Paule Strub Justin W. Taraska |
author_sort | Marco A. Alfonzo-Méndez |
collection | DOAJ |
description | The integration and organization of growth factor signaling, adhesion, and endocytosis is poorly understood. Here the authors use light and electron microscopy to shed light on the role of flat clathrin lattices and cell adhesion in growth factor signaling. |
first_indexed | 2024-12-23T23:53:08Z |
format | Article |
id | doaj.art-e16b28d37d61489b9673c9485b9e1baf |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-23T23:53:08Z |
publishDate | 2022-02-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-e16b28d37d61489b9673c9485b9e1baf2022-12-21T17:25:20ZengNature PortfolioNature Communications2041-17232022-02-0113111610.1038/s41467-022-28373-xDual clathrin and integrin signaling systems regulate growth factor receptor activationMarco A. Alfonzo-Méndez0Kem A. Sochacki1Marie-Paule Strub2Justin W. Taraska3Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of HealthBiochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of HealthBiochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of HealthBiochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of HealthThe integration and organization of growth factor signaling, adhesion, and endocytosis is poorly understood. Here the authors use light and electron microscopy to shed light on the role of flat clathrin lattices and cell adhesion in growth factor signaling.https://doi.org/10.1038/s41467-022-28373-x |
spellingShingle | Marco A. Alfonzo-Méndez Kem A. Sochacki Marie-Paule Strub Justin W. Taraska Dual clathrin and integrin signaling systems regulate growth factor receptor activation Nature Communications |
title | Dual clathrin and integrin signaling systems regulate growth factor receptor activation |
title_full | Dual clathrin and integrin signaling systems regulate growth factor receptor activation |
title_fullStr | Dual clathrin and integrin signaling systems regulate growth factor receptor activation |
title_full_unstemmed | Dual clathrin and integrin signaling systems regulate growth factor receptor activation |
title_short | Dual clathrin and integrin signaling systems regulate growth factor receptor activation |
title_sort | dual clathrin and integrin signaling systems regulate growth factor receptor activation |
url | https://doi.org/10.1038/s41467-022-28373-x |
work_keys_str_mv | AT marcoaalfonzomendez dualclathrinandintegrinsignalingsystemsregulategrowthfactorreceptoractivation AT kemasochacki dualclathrinandintegrinsignalingsystemsregulategrowthfactorreceptoractivation AT mariepaulestrub dualclathrinandintegrinsignalingsystemsregulategrowthfactorreceptoractivation AT justinwtaraska dualclathrinandintegrinsignalingsystemsregulategrowthfactorreceptoractivation |