Renal autoregulation and blood pressure management in circulatory shock
Abstract The importance of personalized blood pressure management is well recognized. Because renal pressure–flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinant...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2018-03-01
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| Series: | Critical Care |
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| Online Access: | http://link.springer.com/article/10.1186/s13054-018-1962-8 |
| _version_ | 1818678280643936256 |
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| author | Emiel Hendrik Post Jean-Louis Vincent |
| author_facet | Emiel Hendrik Post Jean-Louis Vincent |
| author_sort | Emiel Hendrik Post |
| collection | DOAJ |
| description | Abstract The importance of personalized blood pressure management is well recognized. Because renal pressure–flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinants of renal autoregulation in circulatory shock, including the influence of comorbidities and the effects of vasopressor treatment. We review published studies on renal autoregulation relevant to the management of acutely ill patients with shock. We delineate the main signaling pathways of renal autoregulation, discuss how it can be assessed, and describe the renal autoregulatory alterations associated with chronic disease and with shock. |
| first_indexed | 2024-12-17T09:12:46Z |
| format | Article |
| id | doaj.art-e1706e11a4c34c19951f04cac7092ed5 |
| institution | Directory Open Access Journal |
| issn | 1364-8535 |
| language | English |
| last_indexed | 2024-12-17T09:12:46Z |
| publishDate | 2018-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Critical Care |
| spelling | doaj.art-e1706e11a4c34c19951f04cac7092ed52022-12-21T21:55:08ZengBMCCritical Care1364-85352018-03-012211910.1186/s13054-018-1962-8Renal autoregulation and blood pressure management in circulatory shockEmiel Hendrik Post0Jean-Louis Vincent1Department of Intensive Care, Erasme Hospital, Université Libre de BruxellesDepartment of Intensive Care, Erasme Hospital, Université Libre de BruxellesAbstract The importance of personalized blood pressure management is well recognized. Because renal pressure–flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinants of renal autoregulation in circulatory shock, including the influence of comorbidities and the effects of vasopressor treatment. We review published studies on renal autoregulation relevant to the management of acutely ill patients with shock. We delineate the main signaling pathways of renal autoregulation, discuss how it can be assessed, and describe the renal autoregulatory alterations associated with chronic disease and with shock.http://link.springer.com/article/10.1186/s13054-018-1962-8Acute kidney injuryCardiogenic shockHemorrhagic shockRenal blood flowSeptic shock |
| spellingShingle | Emiel Hendrik Post Jean-Louis Vincent Renal autoregulation and blood pressure management in circulatory shock Critical Care Acute kidney injury Cardiogenic shock Hemorrhagic shock Renal blood flow Septic shock |
| title | Renal autoregulation and blood pressure management in circulatory shock |
| title_full | Renal autoregulation and blood pressure management in circulatory shock |
| title_fullStr | Renal autoregulation and blood pressure management in circulatory shock |
| title_full_unstemmed | Renal autoregulation and blood pressure management in circulatory shock |
| title_short | Renal autoregulation and blood pressure management in circulatory shock |
| title_sort | renal autoregulation and blood pressure management in circulatory shock |
| topic | Acute kidney injury Cardiogenic shock Hemorrhagic shock Renal blood flow Septic shock |
| url | http://link.springer.com/article/10.1186/s13054-018-1962-8 |
| work_keys_str_mv | AT emielhendrikpost renalautoregulationandbloodpressuremanagementincirculatoryshock AT jeanlouisvincent renalautoregulationandbloodpressuremanagementincirculatoryshock |