Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy

Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy

G-quadruplex (G4) is the non-canonical secondary structure of DNA and RNA formed by guanine-rich sequences. G4-forming sequences are abundantly located in telomeric regions and in the promoter and untranslated regions (UTR) of cancer-related genes, such as <i>RAS</i> and <i>MYC<...

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Bibliographic Details
Main Authors: Keiko Kawauchi, Ryoto Urano, Natsuki Kinoshita, Shin Kuwamoto, Takeru Torii, Yoshiki Hashimoto, Shinya Taniguchi, Mitsuki Tsuruta, Daisuke Miyoshi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Genes
Subjects:
G-quadruplex
photodynamic therapy
photosensitizer
cancer
telomeres
<i>RAS</i>
Online Access:https://www.mdpi.com/2073-4425/11/11/1340

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