Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity

Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity

Maintaining the excitability of neurons and circuits is fundamental for healthy brain functions. The global compensatory increase in excitatory synaptic strength, in response to decreased activity, is one of the main homeostatic mechanisms responsible for such regulation. This type of plasticity has...

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Bibliographic Details
Main Authors: Federica Cordella, Laura Ferrucci, Chiara D’Antoni, Silvia Ghirga, Carlo Brighi, Alessandro Soloperto, Ylenia Gigante, Davide Ragozzino, Paola Bezzi, Silvia Di Angelantonio
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Life
Subjects:
neurons
plasticity
iPSC
astrocytes
action potential
calcium imaging
Online Access:https://www.mdpi.com/2075-1729/12/11/1884

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