Gene expression of prostaglandin EP4 receptor in three canine carcinomas

Gene expression of prostaglandin EP4 receptor in three canine carcinomas

Abstract Background Chronic inflammation mediated by the cyclooxygenase enzymes, specifically their product prostaglandin E2 (PGE2), can result in the development of cancer. PGE2 promotes cell proliferation, apoptosis, and angiogenesis through interaction with its specific receptors (EP1 receptor -...

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Bibliographic Details
Main Authors: Margaret L. Musser, Austin K. Viall, Rachel L. Phillips, Jesse M. Hostetter, Chad M. Johannes
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Veterinary Research
Subjects:
Cancer
Canine
Carcinoma
Cyclooxygenase enzyme 2
EP4 receptor
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12917-020-02431-2

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