Unique Biomarkers of Collagen Type III Remodeling Reflect Different Information Regarding Pathological Kidney Tissue Alterations in Patients with IgA Nephropathy

Unique Biomarkers of Collagen Type III Remodeling Reflect Different Information Regarding Pathological Kidney Tissue Alterations in Patients with IgA Nephropathy

Kidney fibrosis is the hallmark of chronic kidney disease (CKD) and is characterized by an imbalanced extracellular matrix (ECM) remodeling. Collagen type III is one of the main ECM components of the interstitial matrix of the kidney. We hypothesized that measuring three biomarkers of collagen type...

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Bibliographic Details
Main Authors: Nadja Sparding, Michaela Neprasova, Dita Maixnerova, Federica Genovese, Morten Asser Karsdal, Marek Kollar, Helena Koprivova, Zdenka Hruskova, Vladimir Tesar
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomolecules
Subjects:
biomarker
fibrosis
extracellular matrix
collagen
chronic kidney disease
IgA nephropathy
Online Access:https://www.mdpi.com/2218-273X/13/7/1093

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