Preclinical PET Imaging and Toxicity Study of a <sup>68</sup>Ga-Functionalized Polymeric Cardiac Blood Pool Agent

Preclinical PET Imaging and Toxicity Study of a <sup>68</sup>Ga-Functionalized Polymeric Cardiac Blood Pool Agent

Cardiac blood pool imaging is currently performed almost exclusively with <sup>99m</sup>Tc-based compounds and SPECT/CT imaging. Using a generator-based PET radioisotope has a few advantages, including not needing nuclear reactors to produce it, obtaining better resolution in humans, and...

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Bibliographic Details
Main Authors: Katayoun Saatchi, François Bénard, Navjit Hundal, Joshua Grimes, Sergey Shcherbinin, Maral Pourghiasian, Donald E. Brooks, Anna Celler, Urs O. Häfeli
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
Ga-68
hyperbranched polyglycerol
non-toxic polymer
macromolecule
blood pool imaging agent
PET radiopharmaceutical
Online Access:https://www.mdpi.com/1999-4923/15/3/767

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