In vitro invasion inhibition assay using antibodies against Plasmodium knowlesi Duffy binding protein alpha and apical membrane antigen protein 1 in human erythrocyte-adapted P. knowlesi A1-H.1 strain

In vitro invasion inhibition assay using antibodies against Plasmodium knowlesi Duffy binding protein alpha and apical membrane antigen protein 1 in human erythrocyte-adapted P. knowlesi A1-H.1 strain

Abstract Background The rapid process of malaria erythrocyte invasion involves ligand–receptor interactions. Inducing antibodies against specific ligands or receptors that abrogate the invasion process is a key challenge for blood stage vaccine development. However, few candidates were reported and...

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Bibliographic Details
Main Authors: Fauzi Muh, Seong-Kyun Lee, Mohammad Rafiul Hoque, Jin-Hee Han, Ji-Hoon Park, Egy Rahman Firdaus, Robert W. Moon, Yee Ling Lau, Eun-Taek Han
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Malaria Journal
Subjects:
Plasmodium knowlesi
Zoonotic malaria
PkDBPα
PkAMA1
Invasion
Inhibition
Online Access:http://link.springer.com/article/10.1186/s12936-018-2420-4

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