Characterization of N-Acetyl Cysteine Adducts with Exogenous and Neutrophil-Derived 2-Chlorofatty Aldehyde

Characterization of N-Acetyl Cysteine Adducts with Exogenous and Neutrophil-Derived 2-Chlorofatty Aldehyde

Hypochlorous acid is produced by leukocyte myeloperoxidase activity. 2-Chlorofatty aldehydes (2-ClFALDs) are formed when hypochlorous acid attacks the plasma membrane phospholipid plasmalogen molecular subclass and are thus produced following leukocyte activation as well as in the lungs of mice expo...

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Bibliographic Details
Main Authors:	Shubha Shakya, Reagan M. McGuffee, David A. Ford
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Antioxidants
Subjects:	myeloperoxidase chlorinated lipids N-acetyl cysteine neutrophils
Online Access:	https://www.mdpi.com/2076-3921/12/2/504

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