Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
An open controlled study of efficacy and tolerability of a complex drug Calcemin Advance (CA) in osteopenia in postmenopausal women was performed. 100 women (mean age 58,7±4,5 years) were included. They were randomized into 2 groups. 50 pts of group 1 received CA and 50 pts were included in control...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA PRESS LLC
2008-06-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/800 |
| _version_ | 1797862881908228096 |
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| author | O A Nikitinskaya M Y Toroptsova S G Anikin T A Korotkova N V Demin LA Benevolenskaya |
| author_facet | O A Nikitinskaya M Y Toroptsova S G Anikin T A Korotkova N V Demin LA Benevolenskaya |
| author_sort | O A Nikitinskaya |
| collection | DOAJ |
| description | An open controlled study of efficacy and tolerability of a complex drug Calcemin Advance (CA) in osteopenia in postmenopausal women was performed. 100 women (mean age 58,7±4,5 years) were included. They were randomized into 2 groups. 50 pts of group 1 received CA and 50 pts were included in control group. Bone mineral density (BMD) analysis after 12 months showed stable BMD in pts receiving CA (0,16±4,19%). In control group BMD decreased in all assessed sites, particularly in lumbar spine (-1,63+4,47%, p=0,013). In this group significant decrease of pain was achieved already after 3 months of treatment and was maintained till the end of the study. CA significantly influenced bone remodeling markers. CA is well tolerated. Adverse events appeared in 10% of pts and did not required drug withdrawal. |
| first_indexed | 2024-04-09T22:27:52Z |
| format | Article |
| id | doaj.art-e1764843648040649b8ab9197839c40f |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2024-04-09T22:27:52Z |
| publishDate | 2008-06-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-e1764843648040649b8ab9197839c40f2023-03-22T13:45:44ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922008-06-01463737910.14412/1995-4484-2008-663740Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)O A NikitinskayaM Y ToroptsovaS G AnikinT A KorotkovaN V DeminLA BenevolenskayaAn open controlled study of efficacy and tolerability of a complex drug Calcemin Advance (CA) in osteopenia in postmenopausal women was performed. 100 women (mean age 58,7±4,5 years) were included. They were randomized into 2 groups. 50 pts of group 1 received CA and 50 pts were included in control group. Bone mineral density (BMD) analysis after 12 months showed stable BMD in pts receiving CA (0,16±4,19%). In control group BMD decreased in all assessed sites, particularly in lumbar spine (-1,63+4,47%, p=0,013). In this group significant decrease of pain was achieved already after 3 months of treatment and was maintained till the end of the study. CA significantly influenced bone remodeling markers. CA is well tolerated. Adverse events appeared in 10% of pts and did not required drug withdrawal.https://rsp.mediar-press.net/rsp/article/view/800pmphylaxix of osteoporosisosteopeniacalcemin advance |
| spellingShingle | O A Nikitinskaya M Y Toroptsova S G Anikin T A Korotkova N V Demin LA Benevolenskaya Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study) Научно-практическая ревматология pmphylaxix of osteoporosis osteopenia calcemin advance |
| title | Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study) |
| title_full | Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study) |
| title_fullStr | Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study) |
| title_full_unstemmed | Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study) |
| title_short | Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study) |
| title_sort | prophylaxis of primary osteoporosis in women with complex drug calcemin advance results of an open year s study |
| topic | pmphylaxix of osteoporosis osteopenia calcemin advance |
| url | https://rsp.mediar-press.net/rsp/article/view/800 |
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