Left atrial appendage morphology with the progression of atrial fibrillation

Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transes...

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Main Authors: Yoichi Takaya, Rie Nakayama, Fumi Yokohama, Norihisa Toh, Koji Nakagawa, Masakazu Miyamoto, Hiroshi Ito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/?tool=EBI
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author Yoichi Takaya
Rie Nakayama
Fumi Yokohama
Norihisa Toh
Koji Nakagawa
Masakazu Miyamoto
Hiroshi Ito
author_facet Yoichi Takaya
Rie Nakayama
Fumi Yokohama
Norihisa Toh
Koji Nakagawa
Masakazu Miyamoto
Hiroshi Ito
author_sort Yoichi Takaya
collection DOAJ
description Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transesophageal echocardiography (TEE) were included. Patients were classified into non-AF (n = 64), paroxysmal AF (n = 86), persistent AF (n = 87), or long-standing persistent AF (n = 62). LAA morphology, including LAA ostial diameter and depth, was assessed using TEE. Patients with long-standing persistent AF had larger LAA ostial diameter and depth and lower LAA flow velocity. The maximum LAA ostial diameter was 19 ± 4 mm in patients with non-AF, 21 ± 4 mm in patients with paroxysmal AF, 23 ± 5 mm in patients with persistent AF, and 26 ± 5 mm in patients with long-standing persistent AF. LAA ostial diameter was increased by 2 or 3 mm with the progression of AF. LAA ostial diameter was correlated with LA volume index (R = 0.37, P < 0.01) and the duration of continuous AF (R = 0.30, P < 0.01), but not with age or the period from the onset of AF. In conclusion, LAA size was increased with the progression of AF.
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spelling doaj.art-e179ab5da05a409bb32cebc5c9992a632022-12-22T04:40:52ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-011711Left atrial appendage morphology with the progression of atrial fibrillationYoichi TakayaRie NakayamaFumi YokohamaNorihisa TohKoji NakagawaMasakazu MiyamotoHiroshi ItoLeft atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transesophageal echocardiography (TEE) were included. Patients were classified into non-AF (n = 64), paroxysmal AF (n = 86), persistent AF (n = 87), or long-standing persistent AF (n = 62). LAA morphology, including LAA ostial diameter and depth, was assessed using TEE. Patients with long-standing persistent AF had larger LAA ostial diameter and depth and lower LAA flow velocity. The maximum LAA ostial diameter was 19 ± 4 mm in patients with non-AF, 21 ± 4 mm in patients with paroxysmal AF, 23 ± 5 mm in patients with persistent AF, and 26 ± 5 mm in patients with long-standing persistent AF. LAA ostial diameter was increased by 2 or 3 mm with the progression of AF. LAA ostial diameter was correlated with LA volume index (R = 0.37, P < 0.01) and the duration of continuous AF (R = 0.30, P < 0.01), but not with age or the period from the onset of AF. In conclusion, LAA size was increased with the progression of AF.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/?tool=EBI
spellingShingle Yoichi Takaya
Rie Nakayama
Fumi Yokohama
Norihisa Toh
Koji Nakagawa
Masakazu Miyamoto
Hiroshi Ito
Left atrial appendage morphology with the progression of atrial fibrillation
PLoS ONE
title Left atrial appendage morphology with the progression of atrial fibrillation
title_full Left atrial appendage morphology with the progression of atrial fibrillation
title_fullStr Left atrial appendage morphology with the progression of atrial fibrillation
title_full_unstemmed Left atrial appendage morphology with the progression of atrial fibrillation
title_short Left atrial appendage morphology with the progression of atrial fibrillation
title_sort left atrial appendage morphology with the progression of atrial fibrillation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/?tool=EBI
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