Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

Senescence is the irreversible arrest of cell proliferation that has now been shown to play an important role in both health and disease. With increasing age senescent cells accumulate throughout the body, including the bone marrow and this has been associated with a number of age-related pathologie...

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Bibliographic Details
Main Authors: Charlotte Hellmich, Jamie A. Moore, Kristian M. Bowles, Stuart A. Rushworth
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
senescence
cancer microenvironment
leukemia
p16INK4a
SASP
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00230/full

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