Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis
Acute lung injury (ALI) is a common complication of sepsis with characteristics of acute onset, rapid change in the disease and high mortality. Since current clinical treatment can only alleviate the unfavorable condition to a certain extent but cure, we urgently need to find an effective treatment....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.jadweb.org/article.asp?issn=2221-6189;year=2017;volume=6;issue=6;spage=241;epage=244;aulast=Qian |
| _version_ | 1819231345584373760 |
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| author | Jin Qian Dong-Mei Sun Qi-Feng Huang Xiao-Ran Liu |
| author_facet | Jin Qian Dong-Mei Sun Qi-Feng Huang Xiao-Ran Liu |
| author_sort | Jin Qian |
| collection | DOAJ |
| description | Acute lung injury (ALI) is a common complication of sepsis with characteristics of acute onset, rapid change in the disease and high mortality. Since current clinical treatment can only alleviate the unfavorable condition to a certain extent but cure, we urgently need to find an effective treatment. Most scholars believe that sepsis-induced ALI is associated with extensive mitochondrial damage. In recent years, a widely studied pluripotent stem cell that is mesenchymal stem cell has been proved to alleviate and treat sepsis-induced ALI by transporting mitochondria via nanotubes in a microtubule-dependent manner. Research progress in this field will be reviewed in this study. |
| first_indexed | 2024-12-23T11:43:29Z |
| format | Article |
| id | doaj.art-e183c809d3c340cd8f4d45cea79d8fcf |
| institution | Directory Open Access Journal |
| issn | 2221-6189 2589-5516 |
| language | English |
| last_indexed | 2024-12-23T11:43:29Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-e183c809d3c340cd8f4d45cea79d8fcf2022-12-21T17:48:25ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892589-55162017-01-016624124410.4103/2221-6189.221286Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsisJin QianDong-Mei SunQi-Feng HuangXiao-Ran LiuAcute lung injury (ALI) is a common complication of sepsis with characteristics of acute onset, rapid change in the disease and high mortality. Since current clinical treatment can only alleviate the unfavorable condition to a certain extent but cure, we urgently need to find an effective treatment. Most scholars believe that sepsis-induced ALI is associated with extensive mitochondrial damage. In recent years, a widely studied pluripotent stem cell that is mesenchymal stem cell has been proved to alleviate and treat sepsis-induced ALI by transporting mitochondria via nanotubes in a microtubule-dependent manner. Research progress in this field will be reviewed in this study.http://www.jadweb.org/article.asp?issn=2221-6189;year=2017;volume=6;issue=6;spage=241;epage=244;aulast=QianMesenchymal stem cellsNanotubesMitochondriaSepsisAcute lung injury |
| spellingShingle | Jin Qian Dong-Mei Sun Qi-Feng Huang Xiao-Ran Liu Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis Journal of Acute Disease Mesenchymal stem cells Nanotubes Mitochondria Sepsis Acute lung injury |
| title | Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis |
| title_full | Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis |
| title_fullStr | Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis |
| title_full_unstemmed | Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis |
| title_short | Research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis |
| title_sort | research progress of transfering mitochondria application in nanotubes in treatment of acute lung injury sepsis |
| topic | Mesenchymal stem cells Nanotubes Mitochondria Sepsis Acute lung injury |
| url | http://www.jadweb.org/article.asp?issn=2221-6189;year=2017;volume=6;issue=6;spage=241;epage=244;aulast=Qian |
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