Astaxanthin Activates Nuclear Factor Erythroid-Related Factor 2 and the Antioxidant Responsive Element (Nrf2-ARE) Pathway in the Brain after Subarachnoid Hemorrhage in Rats and Attenuates Early Brain Injury

Astaxanthin Activates Nuclear Factor Erythroid-Related Factor 2 and the Antioxidant Responsive Element (Nrf2-ARE) Pathway in the Brain after Subarachnoid Hemorrhage in Rats and Attenuates Early Brain Injury

Astaxanthin (ATX) has been proven to ameliorate early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH) by modulating cerebral oxidative stress. This study was performed to assess the effect of ATX on the Nrf2-ARE pathway and to explore the underlying molecular mechanisms of antiox...

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Bibliographic Details
Main Authors: Qi Wu, Xiang-Sheng Zhang, Han-Dong Wang, Xin Zhang, Qing Yu, Wei Li, Meng-Liang Zhou, Xiao-Liang Wang
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Marine Drugs
Subjects:
astaxanthin
early brain injury
subarachnoid hemorrhage
nuclear factor erythroid-related factor 2
Online Access:http://www.mdpi.com/1660-3397/12/12/6125

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