Down-regulation of MSH3 and MSH6 genes in female breast cancer patients receiving taxane-based therapy

Down-regulation of MSH3 and MSH6 genes in female breast cancer patients receiving taxane-based therapy

Abstract Background The DNA in each cell in our body is constantly in danger of becoming damaged. Most DNA damage gets repaired straight away via many different proteins encoded by DNA—repair genes. MSH3 and MSH6 are pivotal DNA repair genes maintaining human genome integrity. Dysregulated expressio...

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Bibliographic Details
Main Authors: Hanaa R. M. Attia, Dina F. Ayoub, Shereen H. Abd El-Aziz, Mai M. Abdel Wahed, Safa N. Abd El-Fattah, Mahmoud A. Abdel-Monem, Thanaa M. Rabah, Mahmoud M. Kamel, Amany Helal, Mona Hamed Ibrahim
Format: Article
Language:English
Published: SpringerOpen 2023-10-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Mismatch repair genes
Breast cancer
Taxane-based therapy
Toxicity prediction
Online Access:https://doi.org/10.1186/s43094-023-00549-2

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