A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae

Toshinobu Yokoyama, Jun Sasaki, Keita Matsumoto, Chie Koga, Yusuke Ito, Yoichiro Kaku, Morihiro Tajiri, Hiroki Natori, Masashi HirokawaDivision of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, JapanIntroduction: A necrotic lun...

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Main Authors: Yokoyama T, Sasaki J, Matsumoto K, Koga C, Ito Y, Kaku Y, Tajiri M, Natori H, Hirokawa M
Format: Article
Language:English
Published: Dove Medical Press 2011-12-01
Series:Infection and Drug Resistance
Online Access:http://www.dovepress.com/a-necrotic-lung-ball-caused-by-co-infection-with-candida-and-streptoco-a8879
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author Yokoyama T
Sasaki J
Matsumoto K
Koga C
Ito Y
Kaku Y
Tajiri M
Natori H
Hirokawa M
author_facet Yokoyama T
Sasaki J
Matsumoto K
Koga C
Ito Y
Kaku Y
Tajiri M
Natori H
Hirokawa M
author_sort Yokoyama T
collection DOAJ
description Toshinobu Yokoyama, Jun Sasaki, Keita Matsumoto, Chie Koga, Yusuke Ito, Yoichiro Kaku, Morihiro Tajiri, Hiroki Natori, Masashi HirokawaDivision of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, JapanIntroduction: A necrotic lung ball is a rare radiological feature that is sometimes seen in cases of pulmonary aspergillosis. This paper reports a rare occurrence of a necrotic lung ball in a young male caused by Candida and Streptococcus pneumoniae.Case report: A 28-year-old male with pulmonary candidiasis was found to have a lung ball on computed tomography (CT) of the chest. The patient was treated with ß-lactams and itraconazole and then fluconazole, which improved his condition (as found on a following chest CT scan) and serum ß-D-glucan level. The necrotic lung ball was suspected to have been caused by co-infection with Candida and S. pneumoniae.Conclusion: A necrotic lung ball can result from infection by Candida and/or S. pneumoniae, indicating that physicians should be aware that patients may still have a fungal infection of the lungs that could result in a lung ball, even when they do not have either Aspergillus antibodies or antigens.Keywords: lung ball, necrotic lung ball, Candida, Streptococcus pneumoniae
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spelling doaj.art-e19810b74c5f45d7aeb7b7ce836cc1e72022-12-22T03:23:09ZengDove Medical PressInfection and Drug Resistance1178-69732011-12-012011default221224A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniaeYokoyama TSasaki JMatsumoto KKoga CIto YKaku YTajiri MNatori HHirokawa MToshinobu Yokoyama, Jun Sasaki, Keita Matsumoto, Chie Koga, Yusuke Ito, Yoichiro Kaku, Morihiro Tajiri, Hiroki Natori, Masashi HirokawaDivision of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, JapanIntroduction: A necrotic lung ball is a rare radiological feature that is sometimes seen in cases of pulmonary aspergillosis. This paper reports a rare occurrence of a necrotic lung ball in a young male caused by Candida and Streptococcus pneumoniae.Case report: A 28-year-old male with pulmonary candidiasis was found to have a lung ball on computed tomography (CT) of the chest. The patient was treated with ß-lactams and itraconazole and then fluconazole, which improved his condition (as found on a following chest CT scan) and serum ß-D-glucan level. The necrotic lung ball was suspected to have been caused by co-infection with Candida and S. pneumoniae.Conclusion: A necrotic lung ball can result from infection by Candida and/or S. pneumoniae, indicating that physicians should be aware that patients may still have a fungal infection of the lungs that could result in a lung ball, even when they do not have either Aspergillus antibodies or antigens.Keywords: lung ball, necrotic lung ball, Candida, Streptococcus pneumoniaehttp://www.dovepress.com/a-necrotic-lung-ball-caused-by-co-infection-with-candida-and-streptoco-a8879
spellingShingle Yokoyama T
Sasaki J
Matsumoto K
Koga C
Ito Y
Kaku Y
Tajiri M
Natori H
Hirokawa M
A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
Infection and Drug Resistance
title A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
title_full A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
title_fullStr A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
title_full_unstemmed A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
title_short A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
title_sort necrotic lung ball caused by co infection with candida and streptococcus pneumoniae
url http://www.dovepress.com/a-necrotic-lung-ball-caused-by-co-infection-with-candida-and-streptoco-a8879
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