Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination
Molecular biology applications based on gold nanotechnology have revolutionary impacts, especially in diagnosing and treating molecular and cellular levels. The combination of plasmonic resonance, biochemistry, and optoelectronic engineering has increased the detection of molecules and the possibili...
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Format: | Article |
Language: | English |
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MDPI AG
2023-01-01
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Series: | Molecules |
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Online Access: | https://www.mdpi.com/1420-3049/28/1/364 |
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author | Chien-Hsiu Li Ming-Hsien Chan Yu-Chan Chang Michael Hsiao |
author_facet | Chien-Hsiu Li Ming-Hsien Chan Yu-Chan Chang Michael Hsiao |
author_sort | Chien-Hsiu Li |
collection | DOAJ |
description | Molecular biology applications based on gold nanotechnology have revolutionary impacts, especially in diagnosing and treating molecular and cellular levels. The combination of plasmonic resonance, biochemistry, and optoelectronic engineering has increased the detection of molecules and the possibility of atoms. These advantages have brought medical research to the cellular level for application potential. Many research groups are working towards this. The superior analytical properties of gold nanoparticles can not only be used as an effective drug screening instrument for gene sequencing in new drug development but also as an essential tool for detecting physiological functions, such as blood glucose, antigen-antibody analysis, etc. The review introduces the principles of biomedical sensing systems, the principles of nanomaterial analysis applied to biomedicine at home and abroad, and the chemical surface modification of various gold nanoparticles. |
first_indexed | 2024-03-09T09:44:10Z |
format | Article |
id | doaj.art-e198f164cb9449339189f5845eb6601e |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-03-09T09:44:10Z |
publishDate | 2023-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-e198f164cb9449339189f5845eb6601e2023-12-02T00:42:36ZengMDPI AGMolecules1420-30492023-01-0128136410.3390/molecules28010364Gold Nanoparticles as a Biosensor for Cancer Biomarker DeterminationChien-Hsiu Li0Ming-Hsien Chan1Yu-Chan Chang2Michael Hsiao3Genomics Research Center, Academia Sinica, Taipei 115, TaiwanGenomics Research Center, Academia Sinica, Taipei 115, TaiwanDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, TaiwanGenomics Research Center, Academia Sinica, Taipei 115, TaiwanMolecular biology applications based on gold nanotechnology have revolutionary impacts, especially in diagnosing and treating molecular and cellular levels. The combination of plasmonic resonance, biochemistry, and optoelectronic engineering has increased the detection of molecules and the possibility of atoms. These advantages have brought medical research to the cellular level for application potential. Many research groups are working towards this. The superior analytical properties of gold nanoparticles can not only be used as an effective drug screening instrument for gene sequencing in new drug development but also as an essential tool for detecting physiological functions, such as blood glucose, antigen-antibody analysis, etc. The review introduces the principles of biomedical sensing systems, the principles of nanomaterial analysis applied to biomedicine at home and abroad, and the chemical surface modification of various gold nanoparticles.https://www.mdpi.com/1420-3049/28/1/364gold nanoparticlesbiosensingsurface plasmon resonancecancer markersurface modification |
spellingShingle | Chien-Hsiu Li Ming-Hsien Chan Yu-Chan Chang Michael Hsiao Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination Molecules gold nanoparticles biosensing surface plasmon resonance cancer marker surface modification |
title | Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination |
title_full | Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination |
title_fullStr | Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination |
title_full_unstemmed | Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination |
title_short | Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination |
title_sort | gold nanoparticles as a biosensor for cancer biomarker determination |
topic | gold nanoparticles biosensing surface plasmon resonance cancer marker surface modification |
url | https://www.mdpi.com/1420-3049/28/1/364 |
work_keys_str_mv | AT chienhsiuli goldnanoparticlesasabiosensorforcancerbiomarkerdetermination AT minghsienchan goldnanoparticlesasabiosensorforcancerbiomarkerdetermination AT yuchanchang goldnanoparticlesasabiosensorforcancerbiomarkerdetermination AT michaelhsiao goldnanoparticlesasabiosensorforcancerbiomarkerdetermination |