Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).
Naturally acquired clinical immunity to Plasmodium falciparum is partly mediated by antibodies directed at parasite-derived antigens expressed on the surface of red blood cells which mediate disease and are extremely diverse. Unlike children, adults recognize a broad range of variant surface antigen...
Main Authors: | James Tuju, Margaret J Mackinnon, Abdirahman I Abdi, Henry Karanja, Jennifer N Musyoki, George M Warimwe, Evelyn N Gitau, Kevin Marsh, Peter C Bull, Britta C Urban |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-07-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1007870 |
Similar Items
-
Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
by: Tuju, J, et al.
Published: (2019) -
PfEMP1, polymorphism and pathogenesis.
by: Newbold, C, et al.
Published: (1997) -
Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.
by: Abdi, A, et al.
Published: (2014) -
PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes.
by: Horrocks, P, et al.
Published: (2005) -
PfEMP1 is the major target of antibodies to the surface of P-falciparum-infected erythrocytes that are associated with protection from malaria.
by: Howell, K, et al.
Published: (2008)