World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)

Relevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological characteristics of meningococcal infection. De...

Full description

Bibliographic Details
Main Authors: I. S. Koroleva, M. A. Koroleva
Format: Article
Language:Russian
Published: Numikom LLC 2022-01-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/1405
_version_ 1797879556216979456
author I. S. Koroleva
M. A. Koroleva
author_facet I. S. Koroleva
M. A. Koroleva
author_sort I. S. Koroleva
collection DOAJ
description Relevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological characteristics of meningococcal infection. Despite the high burden of B-meningococcal infection, especially among young children, the design of B-meningococcal vaccines has faced serious difficulties. Aim. The literature review presents the history of the development of B-meningococcal vaccines and provides characteristics of two immunologically effective and safe new generation B-meningococcal vaccine preparations. Conclusion. The licensing of the two new B-meningococcal vaccines presented in the review (Bexsero and Trumenba) was based on immunogenicity and safety. The inclusion of vaccines in national vaccination programs requires careful analysis, including analysis of the antigenic characteristics of circulating strains.
first_indexed 2024-04-10T02:49:23Z
format Article
id doaj.art-e19b2029a9cf48f49a4df8a254441770
institution Directory Open Access Journal
issn 2073-3046
2619-0494
language Russian
last_indexed 2024-04-10T02:49:23Z
publishDate 2022-01-01
publisher Numikom LLC
record_format Article
series Эпидемиология и вакцинопрофилактика
spelling doaj.art-e19b2029a9cf48f49a4df8a2544417702023-03-13T07:43:19ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942022-01-0120610010710.31631/2073-3046-2021-20-6-100-107803World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)I. S. Koroleva0M. A. Koroleva1ФБУН «Центральный научно-исследовательский институт эпидемиологии» РоспотребнадзораФБУН «Центральный научно-исследовательский институт эпидемиологии» РоспотребнадзораRelevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological characteristics of meningococcal infection. Despite the high burden of B-meningococcal infection, especially among young children, the design of B-meningococcal vaccines has faced serious difficulties. Aim. The literature review presents the history of the development of B-meningococcal vaccines and provides characteristics of two immunologically effective and safe new generation B-meningococcal vaccine preparations. Conclusion. The licensing of the two new B-meningococcal vaccines presented in the review (Bexsero and Trumenba) was based on immunogenicity and safety. The inclusion of vaccines in national vaccination programs requires careful analysis, including analysis of the antigenic characteristics of circulating strains.https://www.epidemvac.ru/jour/article/view/1405менингококковая инфекцияв-менингококковая вакцинабелки наружной мембраныгеномные антигены neisseria
spellingShingle I. S. Koroleva
M. A. Koroleva
World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
Эпидемиология и вакцинопрофилактика
менингококковая инфекция
в-менингококковая вакцина
белки наружной мембраны
геномные антигены neisseria
title World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
title_full World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
title_fullStr World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
title_full_unstemmed World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
title_short World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
title_sort world experience in the use serogroup b meningococcal vaccines literature review
topic менингококковая инфекция
в-менингококковая вакцина
белки наружной мембраны
геномные антигены neisseria
url https://www.epidemvac.ru/jour/article/view/1405
work_keys_str_mv AT iskoroleva worldexperienceintheuseserogroupbmeningococcalvaccinesliteraturereview
AT makoroleva worldexperienceintheuseserogroupbmeningococcalvaccinesliteraturereview