World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
Relevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological characteristics of meningococcal infection. De...
Main Authors: | , |
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Format: | Article |
Language: | Russian |
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Numikom LLC
2022-01-01
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Series: | Эпидемиология и вакцинопрофилактика |
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Online Access: | https://www.epidemvac.ru/jour/article/view/1405 |
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author | I. S. Koroleva M. A. Koroleva |
author_facet | I. S. Koroleva M. A. Koroleva |
author_sort | I. S. Koroleva |
collection | DOAJ |
description | Relevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological characteristics of meningococcal infection. Despite the high burden of B-meningococcal infection, especially among young children, the design of B-meningococcal vaccines has faced serious difficulties. Aim. The literature review presents the history of the development of B-meningococcal vaccines and provides characteristics of two immunologically effective and safe new generation B-meningococcal vaccine preparations. Conclusion. The licensing of the two new B-meningococcal vaccines presented in the review (Bexsero and Trumenba) was based on immunogenicity and safety. The inclusion of vaccines in national vaccination programs requires careful analysis, including analysis of the antigenic characteristics of circulating strains. |
first_indexed | 2024-04-10T02:49:23Z |
format | Article |
id | doaj.art-e19b2029a9cf48f49a4df8a254441770 |
institution | Directory Open Access Journal |
issn | 2073-3046 2619-0494 |
language | Russian |
last_indexed | 2024-04-10T02:49:23Z |
publishDate | 2022-01-01 |
publisher | Numikom LLC |
record_format | Article |
series | Эпидемиология и вакцинопрофилактика |
spelling | doaj.art-e19b2029a9cf48f49a4df8a2544417702023-03-13T07:43:19ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942022-01-0120610010710.31631/2073-3046-2021-20-6-100-107803World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)I. S. Koroleva0M. A. Koroleva1ФБУН «Центральный научно-исследовательский институт эпидемиологии» РоспотребнадзораФБУН «Центральный научно-исследовательский институт эпидемиологии» РоспотребнадзораRelevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological characteristics of meningococcal infection. Despite the high burden of B-meningococcal infection, especially among young children, the design of B-meningococcal vaccines has faced serious difficulties. Aim. The literature review presents the history of the development of B-meningococcal vaccines and provides characteristics of two immunologically effective and safe new generation B-meningococcal vaccine preparations. Conclusion. The licensing of the two new B-meningococcal vaccines presented in the review (Bexsero and Trumenba) was based on immunogenicity and safety. The inclusion of vaccines in national vaccination programs requires careful analysis, including analysis of the antigenic characteristics of circulating strains.https://www.epidemvac.ru/jour/article/view/1405менингококковая инфекцияв-менингококковая вакцинабелки наружной мембраныгеномные антигены neisseria |
spellingShingle | I. S. Koroleva M. A. Koroleva World Experience in the Use Serogroup B Meningococcal Vaccines (literature review) Эпидемиология и вакцинопрофилактика менингококковая инфекция в-менингококковая вакцина белки наружной мембраны геномные антигены neisseria |
title | World Experience in the Use Serogroup B Meningococcal Vaccines (literature review) |
title_full | World Experience in the Use Serogroup B Meningococcal Vaccines (literature review) |
title_fullStr | World Experience in the Use Serogroup B Meningococcal Vaccines (literature review) |
title_full_unstemmed | World Experience in the Use Serogroup B Meningococcal Vaccines (literature review) |
title_short | World Experience in the Use Serogroup B Meningococcal Vaccines (literature review) |
title_sort | world experience in the use serogroup b meningococcal vaccines literature review |
topic | менингококковая инфекция в-менингококковая вакцина белки наружной мембраны геномные антигены neisseria |
url | https://www.epidemvac.ru/jour/article/view/1405 |
work_keys_str_mv | AT iskoroleva worldexperienceintheuseserogroupbmeningococcalvaccinesliteraturereview AT makoroleva worldexperienceintheuseserogroupbmeningococcalvaccinesliteraturereview |