Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative
Introgression from wild relatives is a valuable source of novel allelic diversity for breeding. We investigated the genomic patterns of introgression from Aegilops tauschii, the diploid ancestor of the wheat D genome, into winter wheat (Triticum aestivum) cultivars. The population of 351 BC1F3:5 lin...
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| Format: | Article |
| Language: | English |
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Oxford University Press
2020-10-01
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| Series: | G3: Genes, Genomes, Genetics |
| Subjects: | |
| Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.120.401479 |
| _version_ | 1819069918555930624 |
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| author | Moses Nyine Elina Adhikari Marshall Clinesmith Katherine W. Jordan Allan K. Fritz Eduard Akhunov |
| author_facet | Moses Nyine Elina Adhikari Marshall Clinesmith Katherine W. Jordan Allan K. Fritz Eduard Akhunov |
| author_sort | Moses Nyine |
| collection | DOAJ |
| description | Introgression from wild relatives is a valuable source of novel allelic diversity for breeding. We investigated the genomic patterns of introgression from Aegilops tauschii, the diploid ancestor of the wheat D genome, into winter wheat (Triticum aestivum) cultivars. The population of 351 BC1F3:5 lines was selected based on phenology from crosses between six hexaploid wheat lines and 21 wheat-Ae. tauschii octoploids. SNP markers developed for this population and a diverse panel of 116 Ae. tauschii accessions by complexity-reduced genome sequencing were used to detect introgression based on the identity-by-descent analysis. Overall, introgression frequency positively correlated with recombination rate, with a high incidence of introgression at the ends of chromosomes and low in the pericentromeric regions, and was negatively related to sequence divergence between the parental genomes. Reduced introgression in the pericentromeric low-recombining regions spans nearly 2/3 of each chromosome arm, suggestive of the polygenic nature of introgression barriers that could be associated with multilocus negative epistasis between the alleles of wild and cultivated wheat. On the contrary, negative selection against the wild allele of Tg, controlling free-threshing trait and located in the high-recombining chromosomal region, led to reduced introgression only within ∼10 Mbp region around Tg. These results are consistent with the effect of selection on linked variation described by the Hill-Robertson effect, and offer insights into the introgression population development for crop improvement to maximize retention of introgressed diversity across entire genome. |
| first_indexed | 2024-12-21T16:57:41Z |
| format | Article |
| id | doaj.art-e19b5c80a9434ec2ba803a56ae06a442 |
| institution | Directory Open Access Journal |
| issn | 2160-1836 |
| language | English |
| last_indexed | 2024-12-21T16:57:41Z |
| publishDate | 2020-10-01 |
| publisher | Oxford University Press |
| record_format | Article |
| series | G3: Genes, Genomes, Genetics |
| spelling | doaj.art-e19b5c80a9434ec2ba803a56ae06a4422022-12-21T18:56:43ZengOxford University PressG3: Genes, Genomes, Genetics2160-18362020-10-0110103651366110.1534/g3.120.40147918Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild RelativeMoses NyineElina AdhikariMarshall ClinesmithKatherine W. JordanAllan K. FritzEduard AkhunovIntrogression from wild relatives is a valuable source of novel allelic diversity for breeding. We investigated the genomic patterns of introgression from Aegilops tauschii, the diploid ancestor of the wheat D genome, into winter wheat (Triticum aestivum) cultivars. The population of 351 BC1F3:5 lines was selected based on phenology from crosses between six hexaploid wheat lines and 21 wheat-Ae. tauschii octoploids. SNP markers developed for this population and a diverse panel of 116 Ae. tauschii accessions by complexity-reduced genome sequencing were used to detect introgression based on the identity-by-descent analysis. Overall, introgression frequency positively correlated with recombination rate, with a high incidence of introgression at the ends of chromosomes and low in the pericentromeric regions, and was negatively related to sequence divergence between the parental genomes. Reduced introgression in the pericentromeric low-recombining regions spans nearly 2/3 of each chromosome arm, suggestive of the polygenic nature of introgression barriers that could be associated with multilocus negative epistasis between the alleles of wild and cultivated wheat. On the contrary, negative selection against the wild allele of Tg, controlling free-threshing trait and located in the high-recombining chromosomal region, led to reduced introgression only within ∼10 Mbp region around Tg. These results are consistent with the effect of selection on linked variation described by the Hill-Robertson effect, and offer insights into the introgression population development for crop improvement to maximize retention of introgressed diversity across entire genome.http://g3journal.org/lookup/doi/10.1534/g3.120.401479aegilops tauschiiwild relativeintrogressionhexaploid wheatrecombinationtenacious glume |
| spellingShingle | Moses Nyine Elina Adhikari Marshall Clinesmith Katherine W. Jordan Allan K. Fritz Eduard Akhunov Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative G3: Genes, Genomes, Genetics aegilops tauschii wild relative introgression hexaploid wheat recombination tenacious glume |
| title | Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative |
| title_full | Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative |
| title_fullStr | Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative |
| title_full_unstemmed | Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative |
| title_short | Genomic Patterns of Introgression in Interspecific Populations Created by Crossing Wheat with Its Wild Relative |
| title_sort | genomic patterns of introgression in interspecific populations created by crossing wheat with its wild relative |
| topic | aegilops tauschii wild relative introgression hexaploid wheat recombination tenacious glume |
| url | http://g3journal.org/lookup/doi/10.1534/g3.120.401479 |
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