SFRP2 Overexpression Induces an Osteoblast-like Phenotype in Prostate Cancer Cells

SFRP2 Overexpression Induces an Osteoblast-like Phenotype in Prostate Cancer Cells

Prostate cancer bone metastasis is still one of the most fatal cancer diagnoses for men. Survival of the circulating prostate tumor cells and their adaptation strategy to survive in the bone niche is the key point to determining metastasis in early cancer stages. The promoter of <i>SFRP2</i...

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Bibliographic Details
Main Authors: Elif Akova Ölken, Attila Aszodi, Hanna Taipaleenmäki, Hiroaki Saito, Veronika Schönitzer, Michael Chaloupka, Maria Apfelbeck, Wolfgang Böcker, Maximilian Michael Saller
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
SFRP2
osteomimicry
prostate cancer
PC3
bone metastasis
EMT
Online Access:https://www.mdpi.com/2073-4409/11/24/4081

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