Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study

Background and purpose: Red Cell Distribution Width (RDW) is a parameter that measures changes in red blood cell size reported in a complete blood count test. In this study, we aimed to identify the association between RDW and hypertension in Tabari cohort population. Materials and methods: In this...

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Main Authors: Hossein Ranjbaran, Fahimeh Jalalian, Saeed Abediankenari, Mahmood Moosazadeh, Motaharreh Kheradmand
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2022-03-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
Online Access:http://jmums.mazums.ac.ir/article-1-17485-en.html
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author Hossein Ranjbaran
Fahimeh Jalalian
Saeed Abediankenari
Mahmood Moosazadeh
Motaharreh Kheradmand
author_facet Hossein Ranjbaran
Fahimeh Jalalian
Saeed Abediankenari
Mahmood Moosazadeh
Motaharreh Kheradmand
author_sort Hossein Ranjbaran
collection DOAJ
description Background and purpose: Red Cell Distribution Width (RDW) is a parameter that measures changes in red blood cell size reported in a complete blood count test. In this study, we aimed to identify the association between RDW and hypertension in Tabari cohort population. Materials and methods: In this case-control study, case group included all patients with hypertension (n= 2281) participating in Tabari Cohort Study with systolic and diastolic blood pressures more than or equal to 140 and 90, respectively, or those previously diagnosed with hypertension who received antihypertensive drugs. The control group was randomly selected from the Tabari cohort population and matched for sex, age and body mass index. Finally, 2227 people were included in each group. Blood samples were taken from all participants after 12 hours of fasting. Results: Findings showed significant differences between the two groups in all variables studied, including place of residence, level of education, socio-economic status, waist circumference, smoking, and cholesterol level (P<0.05) except triglyceride level (P=0.111). Independent t-test showed that RDW in different quarters was not significantly different between the case group and control group. (P= 0.584). Univariate and multivariate regression tests also did not show a significant relationship between RDW and blood pressure (P>0.05). Conclusion: Our study showed that RDW has no predictive role in hypertension and there is no significant pattern between the range of RDW and hypertension.
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spelling doaj.art-e19f1b9afd7c4c27a417dd6b6c521dcb2023-02-28T07:59:22ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792022-03-01312066369Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control StudyHossein Ranjbaran0Fahimeh Jalalian1Saeed Abediankenari2Mahmood Moosazadeh3Motaharreh Kheradmand4 Assistant Professor, Immunogenetics Research Center, Mazandaran University of Medical Sciences, Sari, Iran Medical Student, Immunogenetics Research Center, Mazandaran University of Medical Sciences, Sari, Iran Professor, Immunogenetics Research Center, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Red Cell Distribution Width (RDW) is a parameter that measures changes in red blood cell size reported in a complete blood count test. In this study, we aimed to identify the association between RDW and hypertension in Tabari cohort population. Materials and methods: In this case-control study, case group included all patients with hypertension (n= 2281) participating in Tabari Cohort Study with systolic and diastolic blood pressures more than or equal to 140 and 90, respectively, or those previously diagnosed with hypertension who received antihypertensive drugs. The control group was randomly selected from the Tabari cohort population and matched for sex, age and body mass index. Finally, 2227 people were included in each group. Blood samples were taken from all participants after 12 hours of fasting. Results: Findings showed significant differences between the two groups in all variables studied, including place of residence, level of education, socio-economic status, waist circumference, smoking, and cholesterol level (P<0.05) except triglyceride level (P=0.111). Independent t-test showed that RDW in different quarters was not significantly different between the case group and control group. (P= 0.584). Univariate and multivariate regression tests also did not show a significant relationship between RDW and blood pressure (P>0.05). Conclusion: Our study showed that RDW has no predictive role in hypertension and there is no significant pattern between the range of RDW and hypertension.http://jmums.mazums.ac.ir/article-1-17485-en.htmlhypertensionred cell distribution widthtabari cohort
spellingShingle Hossein Ranjbaran
Fahimeh Jalalian
Saeed Abediankenari
Mahmood Moosazadeh
Motaharreh Kheradmand
Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study
Journal of Mazandaran University of Medical Sciences
hypertension
red cell distribution width
tabari cohort
title Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study
title_full Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study
title_fullStr Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study
title_full_unstemmed Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study
title_short Association between Red Cell Distribution Width and Hypertension in Tabari Cohort Population: A Case-control Study
title_sort association between red cell distribution width and hypertension in tabari cohort population a case control study
topic hypertension
red cell distribution width
tabari cohort
url http://jmums.mazums.ac.ir/article-1-17485-en.html
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AT saeedabediankenari associationbetweenredcelldistributionwidthandhypertensionintabaricohortpopulationacasecontrolstudy
AT mahmoodmoosazadeh associationbetweenredcelldistributionwidthandhypertensionintabaricohortpopulationacasecontrolstudy
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