The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients
Anemia is a frequent complication in hemodialysis patients. Compared to conventional hemodialysis (CHD), short daily hemodialysis (sDHD) has been reported to be effective in many countries except China. The aim of the present study was to determine whether sDHD could improve anemia and quality of li...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2013-08-01
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| Series: | Brazilian Journal of Medical and Biological Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700629&lng=en&tlng=en |
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| author | J.L. Jiang W. Ren J. Song Q.L. Sun X.Y. Xiao X.Z. Diao Y.H. Huang L. Lan P. Wang Z. Hu |
| author_facet | J.L. Jiang W. Ren J. Song Q.L. Sun X.Y. Xiao X.Z. Diao Y.H. Huang L. Lan P. Wang Z. Hu |
| author_sort | J.L. Jiang |
| collection | DOAJ |
| description | Anemia is a frequent complication in hemodialysis patients. Compared to conventional hemodialysis (CHD), short daily hemodialysis (sDHD) has been reported to be effective in many countries except China. The aim of the present study was to determine whether sDHD could improve anemia and quality of life (QOL) for Chinese outpatients with end-stage renal disease. Twenty-seven patients (16 males/11 females) were converted from CHD to sDHD. All laboratory values were measured before conversion (baseline), at 3 months after conversion (sDHD1), and at 6 months after conversion (sDHD2). The patient's QOL was evaluated at baseline and 6 months after conversion using the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36). Hemoglobin concentration increased significantly from 107.4±7.9 g/L at baseline to 114.4±6.8 g/L (P<0.05) at sDHD1, and 118.3±8.4 g/L (P<0.001) at sDHD2 (Student paired t-test). However, the dose requirement for erythropoietin decreased from 6847.8±1057.3 U/week at baseline to 5869.6±1094.6 U/week (P<0.05) at sDHD2. Weekly stdKt/V increased significantly from 2.05±0.13 at baseline to 2.73±0.20 (P<0.001) at sDHD1, and 2.84±0.26 (P<0.001) at sDHD2. C-reactive protein decreased from baseline to sDHD1 and sDHD2, but without statistically significant differences. Physical and mental health survey scores increased in the 6 months following conversion to sDHD. sDHD may increase hemoglobin levels, decrease exogenous erythropoietin dose requirements, and improve QOL in Chinese hemodialysis patients compared to CHD. A possible mechanism for improvement of clinical outcomes may be optimized management of uremia associated with the higher efficiency of sDHD. |
| first_indexed | 2024-12-20T11:14:23Z |
| format | Article |
| id | doaj.art-e1a1fbaef11d4b909abd6a968a1e7eb4 |
| institution | Directory Open Access Journal |
| issn | 1414-431X |
| language | English |
| last_indexed | 2024-12-20T11:14:23Z |
| publishDate | 2013-08-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-e1a1fbaef11d4b909abd6a968a1e7eb42022-12-21T19:42:40ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research1414-431X2013-08-0146762963310.1590/1414-431X20132832S0100-879X2013000700629The impact of short daily hemodialysis on anemia and the quality of life in Chinese patientsJ.L. JiangW. RenJ. SongQ.L. SunX.Y. XiaoX.Z. DiaoY.H. HuangL. LanP. WangZ. HuAnemia is a frequent complication in hemodialysis patients. Compared to conventional hemodialysis (CHD), short daily hemodialysis (sDHD) has been reported to be effective in many countries except China. The aim of the present study was to determine whether sDHD could improve anemia and quality of life (QOL) for Chinese outpatients with end-stage renal disease. Twenty-seven patients (16 males/11 females) were converted from CHD to sDHD. All laboratory values were measured before conversion (baseline), at 3 months after conversion (sDHD1), and at 6 months after conversion (sDHD2). The patient's QOL was evaluated at baseline and 6 months after conversion using the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36). Hemoglobin concentration increased significantly from 107.4±7.9 g/L at baseline to 114.4±6.8 g/L (P<0.05) at sDHD1, and 118.3±8.4 g/L (P<0.001) at sDHD2 (Student paired t-test). However, the dose requirement for erythropoietin decreased from 6847.8±1057.3 U/week at baseline to 5869.6±1094.6 U/week (P<0.05) at sDHD2. Weekly stdKt/V increased significantly from 2.05±0.13 at baseline to 2.73±0.20 (P<0.001) at sDHD1, and 2.84±0.26 (P<0.001) at sDHD2. C-reactive protein decreased from baseline to sDHD1 and sDHD2, but without statistically significant differences. Physical and mental health survey scores increased in the 6 months following conversion to sDHD. sDHD may increase hemoglobin levels, decrease exogenous erythropoietin dose requirements, and improve QOL in Chinese hemodialysis patients compared to CHD. A possible mechanism for improvement of clinical outcomes may be optimized management of uremia associated with the higher efficiency of sDHD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700629&lng=en&tlng=enShort daily hemodialysisAnemiaErythropoietinQuality of lifeEnd-stage renal disease |
| spellingShingle | J.L. Jiang W. Ren J. Song Q.L. Sun X.Y. Xiao X.Z. Diao Y.H. Huang L. Lan P. Wang Z. Hu The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients Brazilian Journal of Medical and Biological Research Short daily hemodialysis Anemia Erythropoietin Quality of life End-stage renal disease |
| title | The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients |
| title_full | The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients |
| title_fullStr | The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients |
| title_full_unstemmed | The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients |
| title_short | The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients |
| title_sort | impact of short daily hemodialysis on anemia and the quality of life in chinese patients |
| topic | Short daily hemodialysis Anemia Erythropoietin Quality of life End-stage renal disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700629&lng=en&tlng=en |
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