Alzheimer-like brain metabolic and structural features in cholesterol-fed rabbit detected by magnetic resonance imaging

Alzheimer-like brain metabolic and structural features in cholesterol-fed rabbit detected by magnetic resonance imaging

Abstract Background Hypercholesterolemia is known to increase the risk of AD in later life, the purpose of this study is to illustrate brain metabolic and structural changes in a cholesterol-fed rabbit model of Alzheimer’s Disease (AD) by using clinical 3 T Magnetic Resonance Imaging (MRI). Methods...

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Bibliographic Details
Main Authors: Ping Jin, Yongming Pan, Zhiyong Pan, Jianqin Xu, Min Lin, Zhichao Sun, Minli Chen, Maosheng Xu
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Lipids in Health and Disease
Subjects:
Cholesterol
Amyloid β
Rabbit
Magnetic resonance imaging
Magnetic resonance spectroscopy
Brain metabolite
Online Access:http://link.springer.com/article/10.1186/s12944-018-0705-9

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