Design, synthesis, biological evaluation, and bio-computational modeling of imidazo, thieno, pyrimidopyrimidine, pyrimidodiazepene, and motifs as antimicrobial agents

Design, synthesis, biological evaluation, and bio-computational modeling of imidazo, thieno, pyrimidopyrimidine, pyrimidodiazepene, and motifs as antimicrobial agents

In the drug chemistry industry, synthesizing a talented exclusive series of aza-polyheterocyclic compounds was crucial. Aminopyrimidine nucleus reacted with two equivalents of benzaldehyde in the presence of KOH as a starting material to bring about imidazopyrimidine derivative, which experienced in...

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Bibliographic Details
Main Authors:	El-Ahwany Maged F., Assy Mohamed G., Sherif Mohamed H., Soliman Mohamed R., Titi Abderrahim, Touzani Rachid, El-Gendey Marwa S., Shehab Wesam S., Abdellattif Magda H.
Format:	Article
Language:	English
Published:	De Gruyter 2023-08-01
Series:	Heterocyclic Communications
Subjects:	imidazopyrimidine thienopyrimidine pyrimidopyrimidine pyrimidodiazepene molecular docking pom studies
Online Access:	https://doi.org/10.1515/hc-2022-0156

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