Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest

Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest

Cardiac arrest (CA) causes high mortality due to multi-system organ damage attributable to ischemia-reperfusion injury. Recent work in our group found that among diabetic patients who experienced cardiac arrest, those taking metformin had less evidence of cardiac and renal damage after cardiac arres...

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Bibliographic Details
Main Authors: Cody A. Rutledge, Claudia Lagranha, Takuto Chiba, Kevin Redding, Donna B. Stolz, Eric Goetzman, Sunder Sims-Lucas, Brett A. Kaufman
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Molecular and Cellular Cardiology Plus
Subjects:
Metformin
Cardiac arrest
AMPK
Myocardial stunning
Online Access:http://www.sciencedirect.com/science/article/pii/S2772976123000041

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