The interaction of classical complement component C1 with parasite and host calreticulin mediates Trypanosoma cruzi infection of human placenta.

BACKGROUND: 9 million people are infected with Trypanosoma cruzi in Latin America, plus more than 300,000 in the United States, Canada, Europe, Australia, and Japan. Approximately 30% of infected individuals develop circulatory or digestive pathology. While in underdeveloped countries transmission i...

Full description

Bibliographic Details
Main Authors: Christian Castillo, Galia Ramírez, Carolina Valck, Lorena Aguilar, Ismael Maldonado, Carlos Rosas, Norbel Galanti, Ulrike Kemmerling, Arturo Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3749977?pdf=render