RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation

Bibliographic Details
Main Authors: Li-Jun Song, Xu-Ren Yin, Sheng-Wen Guan, Hong Gao, Pan-Pan Dong, Cong-Jin Mei, Ying-Ying Yang, Ying Zhang, Chuan-Xin Yu, Zi-Chun Hua
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01019-6
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author Li-Jun Song
Xu-Ren Yin
Sheng-Wen Guan
Hong Gao
Pan-Pan Dong
Cong-Jin Mei
Ying-Ying Yang
Ying Zhang
Chuan-Xin Yu
Zi-Chun Hua
author_facet Li-Jun Song
Xu-Ren Yin
Sheng-Wen Guan
Hong Gao
Pan-Pan Dong
Cong-Jin Mei
Ying-Ying Yang
Ying Zhang
Chuan-Xin Yu
Zi-Chun Hua
author_sort Li-Jun Song
collection DOAJ
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publishDate 2022-06-01
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series Signal Transduction and Targeted Therapy
spelling doaj.art-e1af536559534d5999bc92f33b740a292022-12-22T02:41:23ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352022-06-01711310.1038/s41392-022-01019-6RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulationLi-Jun Song0Xu-Ren Yin1Sheng-Wen Guan2Hong Gao3Pan-Pan Dong4Cong-Jin Mei5Ying-Ying Yang6Ying Zhang7Chuan-Xin Yu8Zi-Chun Hua9School of Life Sciences and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing UniversityKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic DiseasesSchool of Life Sciences and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing UniversityDepartment of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical SchoolKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic DiseasesKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic DiseasesKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic DiseasesKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic DiseasesKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic DiseasesSchool of Life Sciences and the State Key Laboratory of Pharmaceutical Biotechnology, Nanjing Universityhttps://doi.org/10.1038/s41392-022-01019-6
spellingShingle Li-Jun Song
Xu-Ren Yin
Sheng-Wen Guan
Hong Gao
Pan-Pan Dong
Cong-Jin Mei
Ying-Ying Yang
Ying Zhang
Chuan-Xin Yu
Zi-Chun Hua
RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation
Signal Transduction and Targeted Therapy
title RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation
title_full RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation
title_fullStr RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation
title_full_unstemmed RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation
title_short RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation
title_sort rip3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through jnk cjun egr1 downregulation
url https://doi.org/10.1038/s41392-022-01019-6
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