Evolutionary and developmental modules
The identification of biological modules at the systems level often follows top‐down decomposition of atask goal, or bottom‐up decomposition of multidimensional data arrays into basic elements or patternsrepresenting shared features. These approaches traditionally have been applied to mature, fullyd...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-05-01
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| Series: | Frontiers in Computational Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncom.2013.00061/full |
| _version_ | 1819085318101401600 |
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| author | Francesco eLacquaniti Francesco eLacquaniti Francesco eLacquaniti Yuri P Ivanenko Andrea eD'avella Karl eZelik Myrka eZago |
| author_facet | Francesco eLacquaniti Francesco eLacquaniti Francesco eLacquaniti Yuri P Ivanenko Andrea eD'avella Karl eZelik Myrka eZago |
| author_sort | Francesco eLacquaniti |
| collection | DOAJ |
| description | The identification of biological modules at the systems level often follows top‐down decomposition of atask goal, or bottom‐up decomposition of multidimensional data arrays into basic elements or patternsrepresenting shared features. These approaches traditionally have been applied to mature, fullydeveloped systems. Here we review some results from two other perspectives on modularity, namelythe developmental and evolutionary perspective. There is growing evidence that modular units ofdevelopment were highly preserved and recombined during evolution. We first consider a few examplesof modules well identifiable from morphology. Next we consider the more difficult issue of identifyingfunctional developmental modules. We dwell especially on modular control of locomotion to argue thatthe building blocks used to construct different locomotor behaviors are similar across several animalspecies, presumably related to ancestral neural networks of command. A recurrent theme fromcomparative studies is that the developmental addition of new premotor modules underlies thepostnatal acquisition and refinement of several different motor behaviors in vertebrates. |
| first_indexed | 2024-12-21T21:02:27Z |
| format | Article |
| id | doaj.art-e1afc229d8b14740bc4161dcecd54cf4 |
| institution | Directory Open Access Journal |
| issn | 1662-5188 |
| language | English |
| last_indexed | 2024-12-21T21:02:27Z |
| publishDate | 2013-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Computational Neuroscience |
| spelling | doaj.art-e1afc229d8b14740bc4161dcecd54cf42022-12-21T18:50:25ZengFrontiers Media S.A.Frontiers in Computational Neuroscience1662-51882013-05-01710.3389/fncom.2013.0006150001Evolutionary and developmental modulesFrancesco eLacquaniti0Francesco eLacquaniti1Francesco eLacquaniti2Yuri P Ivanenko3Andrea eD'avella4Karl eZelik5Myrka eZago6University of Rome Tor VergataUniversity of Rome Tor VergataIRCCS Fondazione Santa LuciaIRCCS Fondazione Santa LuciaIRCCS Fondazione Santa LuciaIRCCS Fondazione Santa LuciaIRCCS Fondazione Santa LuciaThe identification of biological modules at the systems level often follows top‐down decomposition of atask goal, or bottom‐up decomposition of multidimensional data arrays into basic elements or patternsrepresenting shared features. These approaches traditionally have been applied to mature, fullydeveloped systems. Here we review some results from two other perspectives on modularity, namelythe developmental and evolutionary perspective. There is growing evidence that modular units ofdevelopment were highly preserved and recombined during evolution. We first consider a few examplesof modules well identifiable from morphology. Next we consider the more difficult issue of identifyingfunctional developmental modules. We dwell especially on modular control of locomotion to argue thatthe building blocks used to construct different locomotor behaviors are similar across several animalspecies, presumably related to ancestral neural networks of command. A recurrent theme fromcomparative studies is that the developmental addition of new premotor modules underlies thepostnatal acquisition and refinement of several different motor behaviors in vertebrates.http://journal.frontiersin.org/Journal/10.3389/fncom.2013.00061/fullGene ExpressionInterneuronsLocomotionCpGactivation pattern |
| spellingShingle | Francesco eLacquaniti Francesco eLacquaniti Francesco eLacquaniti Yuri P Ivanenko Andrea eD'avella Karl eZelik Myrka eZago Evolutionary and developmental modules Frontiers in Computational Neuroscience Gene Expression Interneurons Locomotion CpG activation pattern |
| title | Evolutionary and developmental modules |
| title_full | Evolutionary and developmental modules |
| title_fullStr | Evolutionary and developmental modules |
| title_full_unstemmed | Evolutionary and developmental modules |
| title_short | Evolutionary and developmental modules |
| title_sort | evolutionary and developmental modules |
| topic | Gene Expression Interneurons Locomotion CpG activation pattern |
| url | http://journal.frontiersin.org/Journal/10.3389/fncom.2013.00061/full |
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