The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

Summary: Endoplasmic reticulum (ER) stress is transmitted to mitochondria and is associated with pathologic mitochondrial dysfunction in diverse diseases. The PERK arm of the unfolded protein response (UPR) protects mitochondria during ER stress through the transcriptional and translational remodeli...

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Bibliographic Details
Main Authors:	Justine Lebeau, Jaclyn M. Saunders, Vivian W.R. Moraes, Aparajita Madhavan, Nicole Madrazo, Mary C. Anthony, R. Luke Wiseman
Format:	Article
Language:	English
Published:	Elsevier 2018-03-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124718302493

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