The use of single armed observational data to closing the gap in otherwise disconnected evidence networks: a network meta-analysis in multiple myeloma

The use of single armed observational data to closing the gap in otherwise disconnected evidence networks: a network meta-analysis in multiple myeloma

Abstract Background Network meta-analysis (NMA) allows for the estimation of comparative effectiveness of treatments that have not been studied in head-to-head trials; however, relative treatment effects for all interventions can only be derived where available evidence forms a connected network. He...

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Bibliographic Details
Main Authors: Susanne Schmitz, Áine Maguire, James Morris, Kai Ruggeri, Elisa Haller, Isla Kuhn, Joy Leahy, Natalia Homer, Ayesha Khan, Jack Bowden, Vanessa Buchanan, Michael O’Dwyer, Gordon Cook, Cathal Walsh
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Medical Research Methodology
Subjects:
Network meta-analysis
Single armed studies
Evidence synthesis
Relapsed or refractory myeloma
Online Access:http://link.springer.com/article/10.1186/s12874-018-0509-7

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