Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors
ObjectiveThis study examined the potential of combining Doppler ultrasound (DUS) and CT angiography (CTA) for early detection and intervention of lower extremity arterial disease (LEAD) in diabetes.Concurrently, risk factors influencing LEAD progression were analyzed.Methods106 Type-2 diabetes patie...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1257241/full |
| _version_ | 1827369156233658368 |
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| author | ShaoRui Zhang Yan Wu YuQing Guo XinJu Jia Yan Kang XueLian Shen Jia Song AiGe Yang |
| author_facet | ShaoRui Zhang Yan Wu YuQing Guo XinJu Jia Yan Kang XueLian Shen Jia Song AiGe Yang |
| author_sort | ShaoRui Zhang |
| collection | DOAJ |
| description | ObjectiveThis study examined the potential of combining Doppler ultrasound (DUS) and CT angiography (CTA) for early detection and intervention of lower extremity arterial disease (LEAD) in diabetes.Concurrently, risk factors influencing LEAD progression were analyzed.Methods106 Type-2 diabetes patients with LEAD, having undergone DUS and CTA, were divided into four stages according to Fontaine stage. Results of DUS and CTA were compared across stages and potential risk factors were analyzed.ResultsPositive detection rates of LEAD differed between DUS and CTA for Fontaine stages I and II (P < 0.05), with no significant difference for stages III and IV (P > 0.05). CTA identified subgroups with mild to moderate stenosis and severe stenosis or occlusion, with positive rates on DUS of 17.95% and 89.9% respectively. Hypertension was found as an independent risk factor affecting LEAD progression.ConclusionCTA should be performed early for LEAD in diabetes patients at Fontaine stages I and II, regardless of DUS results. For diabetes patients with LEAD, stringent blood pressure control is crucial to delay disease progression. |
| first_indexed | 2024-03-08T09:42:13Z |
| format | Article |
| id | doaj.art-e1c14f245b534463ac0126486e8fbead |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-08T09:42:13Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-e1c14f245b534463ac0126486e8fbead2024-01-30T04:25:46ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-01-011410.3389/fendo.2023.12572411257241Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factorsShaoRui Zhang0Yan Wu1YuQing Guo2XinJu Jia3Yan Kang4XueLian Shen5Jia Song6AiGe Yang7Department of Nutrition, The First Hospital of Zhangjiakou, Zhangjiakou, Hebei, ChinaDepartment of Clinical Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaDepartment of Endocrinology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, ChinaObjectiveThis study examined the potential of combining Doppler ultrasound (DUS) and CT angiography (CTA) for early detection and intervention of lower extremity arterial disease (LEAD) in diabetes.Concurrently, risk factors influencing LEAD progression were analyzed.Methods106 Type-2 diabetes patients with LEAD, having undergone DUS and CTA, were divided into four stages according to Fontaine stage. Results of DUS and CTA were compared across stages and potential risk factors were analyzed.ResultsPositive detection rates of LEAD differed between DUS and CTA for Fontaine stages I and II (P < 0.05), with no significant difference for stages III and IV (P > 0.05). CTA identified subgroups with mild to moderate stenosis and severe stenosis or occlusion, with positive rates on DUS of 17.95% and 89.9% respectively. Hypertension was found as an independent risk factor affecting LEAD progression.ConclusionCTA should be performed early for LEAD in diabetes patients at Fontaine stages I and II, regardless of DUS results. For diabetes patients with LEAD, stringent blood pressure control is crucial to delay disease progression.https://www.frontiersin.org/articles/10.3389/fendo.2023.1257241/fulltype 2 diabeteslower extremity arterialangiographyDoppler ultrasoundapplication opportunity |
| spellingShingle | ShaoRui Zhang Yan Wu YuQing Guo XinJu Jia Yan Kang XueLian Shen Jia Song AiGe Yang Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors Frontiers in Endocrinology type 2 diabetes lower extremity arterial angiography Doppler ultrasound application opportunity |
| title | Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors |
| title_full | Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors |
| title_fullStr | Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors |
| title_full_unstemmed | Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors |
| title_short | Application opportunity of Doppler ultrasound combined with CT angiography in diabetic lower extremity arterial disease and the analysis of the risk factors |
| title_sort | application opportunity of doppler ultrasound combined with ct angiography in diabetic lower extremity arterial disease and the analysis of the risk factors |
| topic | type 2 diabetes lower extremity arterial angiography Doppler ultrasound application opportunity |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1257241/full |
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