Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders

IntroductionAttention Deficit Hyperactivity Disorder (ADHD) is found in up to 20% adults with Substance Use Disorder (SUD). ADHD + SUD is associated with a more complex clinical presentation and poorer outcomes than each disorder alone. In the presence of SUD, adult ADHD is particularly difficult to...

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Main Authors: Norman Therribout, Emily Karsinti, Alix Morel, Alexandra Dereux, Florence Vorspan, Lucia Romo, Romain Icick
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.803227/full
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author Norman Therribout
Norman Therribout
Norman Therribout
Norman Therribout
Emily Karsinti
Emily Karsinti
Emily Karsinti
Emily Karsinti
Alix Morel
Alix Morel
Alix Morel
Alexandra Dereux
Alexandra Dereux
Alexandra Dereux
Florence Vorspan
Florence Vorspan
Florence Vorspan
Lucia Romo
Lucia Romo
Lucia Romo
Romain Icick
Romain Icick
Romain Icick
author_facet Norman Therribout
Norman Therribout
Norman Therribout
Norman Therribout
Emily Karsinti
Emily Karsinti
Emily Karsinti
Emily Karsinti
Alix Morel
Alix Morel
Alix Morel
Alexandra Dereux
Alexandra Dereux
Alexandra Dereux
Florence Vorspan
Florence Vorspan
Florence Vorspan
Lucia Romo
Lucia Romo
Lucia Romo
Romain Icick
Romain Icick
Romain Icick
author_sort Norman Therribout
collection DOAJ
description IntroductionAttention Deficit Hyperactivity Disorder (ADHD) is found in up to 20% adults with Substance Use Disorder (SUD). ADHD + SUD is associated with a more complex clinical presentation and poorer outcomes than each disorder alone. In the presence of SUD, adult ADHD is particularly difficult to diagnose as both disorders can mimic or hide the symptoms of each other. Our university hospital in Paris recently started an extensive outpatient diagnostic procedure for adult patients with SUD to ascertain or refute ADHD diagnosis and to provide therapeutic guidance. Here, we report the acceptability of the assessment procedure for patients and the preliminary description of the current and lifetime clinical profiles as a function of the final diagnosis “ADHD vs. no ADHD.”MethodAdult SUD patients with suspected ADHD were included in the current pilot study after stating they had no objection that their de-identified data were used for research purposes, according to French ethical procedures. Patients were evaluated for ADHD, comorbid mental disorders, cognitive state and dimensional psychological variables. They were assessed by trained psychologists and psychiatrists using standardized tools over a day. ADHD diagnosis was mainly based on the Diagnostisch Interview Voor ADHD for DSM-5 (DIVA-5).ResultsOut of 18 eligible patients, 17 were included in the cohort (1 excluded) and none was opposed to using their data. Thirteen (76%) participants were diagnosed with ADHD. All patients appointed for the ADHD diagnostic procedure came, respected schedules and finished the evaluation. All patients were impaired on cognitive functioning and were highly comorbid, but ADHD patients seems to suffer even more from those conditions, especially for cannabis and stimulant use disorders.DiscussionPreliminary results show high acceptability of the procedure by ADHD-SUD patients. This result could be explained by all the organization adapted to the psychopathology. Patients' baseline motivation to participate also represents an uncontrolled variable that could promote the ability to follow the procedure. Acceptance results of the protocol are promising and represent a starting point to identify the best procedures to design patient-centered pharmacological and non-pharmacological therapies.
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spelling doaj.art-e1c282b45dde4fb1be20f7c0fa38ce0a2022-12-22T02:32:43ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-06-011310.3389/fpsyt.2022.803227803227Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use DisordersNorman Therribout0Norman Therribout1Norman Therribout2Norman Therribout3Emily Karsinti4Emily Karsinti5Emily Karsinti6Emily Karsinti7Alix Morel8Alix Morel9Alix Morel10Alexandra Dereux11Alexandra Dereux12Alexandra Dereux13Florence Vorspan14Florence Vorspan15Florence Vorspan16Lucia Romo17Lucia Romo18Lucia Romo19Romain Icick20Romain Icick21Romain Icick22Assistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, Département Universitaire de Psychiatrie et de Médecine Addictologique, Paris, FranceUniversité de Paris Cité, INSERM UMR-S1144, Paris, FranceLaboratoire Clipsyd EA 4430, Université Paris-Nanterre, Nanterre, FranceFHU NOR-SUD Network of Research in Substance Use Disorders, Paris, FranceAssistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, Département Universitaire de Psychiatrie et de Médecine Addictologique, Paris, FranceUniversité de Paris Cité, INSERM UMR-S1144, Paris, FranceLaboratoire Clipsyd EA 4430, Université Paris-Nanterre, Nanterre, FranceFHU NOR-SUD Network of Research in Substance Use Disorders, Paris, FranceAssistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, Département Universitaire de Psychiatrie et de Médecine Addictologique, Paris, FranceUniversité de Paris Cité, INSERM UMR-S1144, Paris, FranceFHU NOR-SUD Network of Research in Substance Use Disorders, Paris, FranceAssistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, Département Universitaire de Psychiatrie et de Médecine Addictologique, Paris, FranceUniversité de Paris Cité, INSERM UMR-S1144, Paris, FranceFHU NOR-SUD Network of Research in Substance Use Disorders, Paris, FranceAssistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, Département Universitaire de Psychiatrie et de Médecine Addictologique, Paris, FranceUniversité de Paris Cité, INSERM UMR-S1144, Paris, FranceFHU NOR-SUD Network of Research in Substance Use Disorders, Paris, FranceLaboratoire Clipsyd EA 4430, Université Paris-Nanterre, Nanterre, FranceAssistance Publique – Hôpitaux de Paris, Hôpital Raymond-Poincaré, Garches, FranceCESP, U1018 INSERM UPS UVSQ, Villejuif, FranceAssistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, Département Universitaire de Psychiatrie et de Médecine Addictologique, Paris, FranceUniversité de Paris Cité, INSERM UMR-S1144, Paris, FranceFHU NOR-SUD Network of Research in Substance Use Disorders, Paris, FranceIntroductionAttention Deficit Hyperactivity Disorder (ADHD) is found in up to 20% adults with Substance Use Disorder (SUD). ADHD + SUD is associated with a more complex clinical presentation and poorer outcomes than each disorder alone. In the presence of SUD, adult ADHD is particularly difficult to diagnose as both disorders can mimic or hide the symptoms of each other. Our university hospital in Paris recently started an extensive outpatient diagnostic procedure for adult patients with SUD to ascertain or refute ADHD diagnosis and to provide therapeutic guidance. Here, we report the acceptability of the assessment procedure for patients and the preliminary description of the current and lifetime clinical profiles as a function of the final diagnosis “ADHD vs. no ADHD.”MethodAdult SUD patients with suspected ADHD were included in the current pilot study after stating they had no objection that their de-identified data were used for research purposes, according to French ethical procedures. Patients were evaluated for ADHD, comorbid mental disorders, cognitive state and dimensional psychological variables. They were assessed by trained psychologists and psychiatrists using standardized tools over a day. ADHD diagnosis was mainly based on the Diagnostisch Interview Voor ADHD for DSM-5 (DIVA-5).ResultsOut of 18 eligible patients, 17 were included in the cohort (1 excluded) and none was opposed to using their data. Thirteen (76%) participants were diagnosed with ADHD. All patients appointed for the ADHD diagnostic procedure came, respected schedules and finished the evaluation. All patients were impaired on cognitive functioning and were highly comorbid, but ADHD patients seems to suffer even more from those conditions, especially for cannabis and stimulant use disorders.DiscussionPreliminary results show high acceptability of the procedure by ADHD-SUD patients. This result could be explained by all the organization adapted to the psychopathology. Patients' baseline motivation to participate also represents an uncontrolled variable that could promote the ability to follow the procedure. Acceptance results of the protocol are promising and represent a starting point to identify the best procedures to design patient-centered pharmacological and non-pharmacological therapies.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.803227/fulldiagnosisacceptabilitystimulantcognitivecocaineattention deficit-hyperactivity disorder (ADHD)
spellingShingle Norman Therribout
Norman Therribout
Norman Therribout
Norman Therribout
Emily Karsinti
Emily Karsinti
Emily Karsinti
Emily Karsinti
Alix Morel
Alix Morel
Alix Morel
Alexandra Dereux
Alexandra Dereux
Alexandra Dereux
Florence Vorspan
Florence Vorspan
Florence Vorspan
Lucia Romo
Lucia Romo
Lucia Romo
Romain Icick
Romain Icick
Romain Icick
Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders
Frontiers in Psychiatry
diagnosis
acceptability
stimulant
cognitive
cocaine
attention deficit-hyperactivity disorder (ADHD)
title Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders
title_full Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders
title_fullStr Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders
title_full_unstemmed Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders
title_short Feasibility of an Extensive Strategy for Adult Diagnosis of Attention Deficit Hyperactivity Disorder Among Patients Suffering From Substance Use Disorders
title_sort feasibility of an extensive strategy for adult diagnosis of attention deficit hyperactivity disorder among patients suffering from substance use disorders
topic diagnosis
acceptability
stimulant
cognitive
cocaine
attention deficit-hyperactivity disorder (ADHD)
url https://www.frontiersin.org/articles/10.3389/fpsyt.2022.803227/full
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