Causal Effects of Genetically Predicted Cystatin C on Osteoporosis: A Two-Sample Mendelian Randomization Study

Causal Effects of Genetically Predicted Cystatin C on Osteoporosis: A Two-Sample Mendelian Randomization Study

Objectives: Although it has long been reported that high levels of cystatin C could contribute to the development of osteoporosis in some studies, no evidence has established a causal association between them thus far.Methods: A Mendelian randomization (MR) study was conducted to determine the causa...

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Bibliographic Details
Main Authors: Jiaqin Yuan, Lipeng Peng, Fujun Luan, Jie Li, Jinglin Zhang, Wei Jiang, Wenting Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
mendelian randomization
cystatin C
osteoporosis
genetics
bone mineral density
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.849206/full

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