In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves
The cornea is the optical window to the brain. Its optical and structural properties are responsible for optical transparency and vision. The shape, elasticity, rigidity, or stiffness are due to its biomechanical properties, whose stability results in ocular integrity and intraocular pressure dynami...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Optics |
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| Online Access: | https://www.mdpi.com/2673-3269/4/4/43 |
| _version_ | 1797379813766332416 |
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| author | Francisco J. Ávila Maria Concepción Marcellán Laura Remón |
| author_facet | Francisco J. Ávila Maria Concepción Marcellán Laura Remón |
| author_sort | Francisco J. Ávila |
| collection | DOAJ |
| description | The cornea is the optical window to the brain. Its optical and structural properties are responsible for optical transparency and vision. The shape, elasticity, rigidity, or stiffness are due to its biomechanical properties, whose stability results in ocular integrity and intraocular pressure dynamics. Here, we report in vivo observations of shape changes and biomechanical alterations in the human cornea induced by acoustic wave pressure within the frequency range of 50–350 Hz and the sound pressure level of 90 dB. The central corneal thickness (CCT) and eccentricity (e<sup>2</sup>) were measured using Scheimpflug imaging and biomechanical properties [corneal hysteresis (CH) and intraocular pressure (IOP)] were assessed with air-puff tonometry in six young, healthy volunteers. At the specific 150 Hz acoustic frequency, the variations in e<sup>2</sup> and CCT were 0.058 and 7.33 µm, respectively. Biomechanical alterations were also observed in both the IOP (a decrease of 3.60 mmHg) and CH (an increase of 0.40 mmHg). |
| first_indexed | 2024-03-08T20:28:28Z |
| format | Article |
| id | doaj.art-e1c384d886d94e5ca2e5951da1173a69 |
| institution | Directory Open Access Journal |
| issn | 2673-3269 |
| language | English |
| last_indexed | 2024-03-08T20:28:28Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Optics |
| spelling | doaj.art-e1c384d886d94e5ca2e5951da1173a692023-12-22T14:30:29ZengMDPI AGOptics2673-32692023-11-014458459410.3390/opt4040043In Vivo Biomechanical Response of the Human Cornea to Acoustic WavesFrancisco J. Ávila0Maria Concepción Marcellán1Laura Remón2Departamento de Física Aplicada, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, SpainDepartamento de Física Aplicada, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, SpainDepartamento de Física Aplicada, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, SpainThe cornea is the optical window to the brain. Its optical and structural properties are responsible for optical transparency and vision. The shape, elasticity, rigidity, or stiffness are due to its biomechanical properties, whose stability results in ocular integrity and intraocular pressure dynamics. Here, we report in vivo observations of shape changes and biomechanical alterations in the human cornea induced by acoustic wave pressure within the frequency range of 50–350 Hz and the sound pressure level of 90 dB. The central corneal thickness (CCT) and eccentricity (e<sup>2</sup>) were measured using Scheimpflug imaging and biomechanical properties [corneal hysteresis (CH) and intraocular pressure (IOP)] were assessed with air-puff tonometry in six young, healthy volunteers. At the specific 150 Hz acoustic frequency, the variations in e<sup>2</sup> and CCT were 0.058 and 7.33 µm, respectively. Biomechanical alterations were also observed in both the IOP (a decrease of 3.60 mmHg) and CH (an increase of 0.40 mmHg).https://www.mdpi.com/2673-3269/4/4/43corneal biomechanicscorneal resonanceacoustic vibrometry |
| spellingShingle | Francisco J. Ávila Maria Concepción Marcellán Laura Remón In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves Optics corneal biomechanics corneal resonance acoustic vibrometry |
| title | In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves |
| title_full | In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves |
| title_fullStr | In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves |
| title_full_unstemmed | In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves |
| title_short | In Vivo Biomechanical Response of the Human Cornea to Acoustic Waves |
| title_sort | in vivo biomechanical response of the human cornea to acoustic waves |
| topic | corneal biomechanics corneal resonance acoustic vibrometry |
| url | https://www.mdpi.com/2673-3269/4/4/43 |
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