Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
We made complex immunehistology ex amination of local immune system of segmental bronchus for 54 patients with chronic obstructive pulmonary disease. In the article author give principles about allocation and quantitative index for immunocompetent cells. We ascert ained correlation between level of...
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Format: | Article |
Language: | Russian |
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Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy
2012-01-01
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Series: | Морфологія |
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Online Access: | http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12mlsozl.pdf |
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author | Malofiy L.S. |
author_facet | Malofiy L.S. |
author_sort | Malofiy L.S. |
collection | DOAJ |
description | We made complex immunehistology ex amination of local immune system of segmental bronchus for 54 patients with chronic obstructive pulmonary disease. In the article author give principles about allocation and quantitative index for immunocompetent cells. We ascert ained correlation between level of expression, stage and clinic al course of disease. Our examination demonstrated ambiguous fate for local immunity cells duri ng formation of pathogenetical aspects about chronic obstructive pulmonary disease progress. There is a pronounced disbalance of immunoregulatory index. The predominance of cytotoxic lymphocytes is observed in the foci of disregeneration processes, namely, in proliferation, hyperpla-sia, squamous metaplasia and dysp lasia of the bronchial epithelium. |
first_indexed | 2024-12-10T11:55:12Z |
format | Article |
id | doaj.art-e1c4a967619f4a7ca3e389d9e86a6073 |
institution | Directory Open Access Journal |
issn | 1997-9665 |
language | Russian |
last_indexed | 2024-12-10T11:55:12Z |
publishDate | 2012-01-01 |
publisher | Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy |
record_format | Article |
series | Морфологія |
spelling | doaj.art-e1c4a967619f4a7ca3e389d9e86a60732022-12-22T01:49:49ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96652012-01-01613742Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary diseaseMalofiy L.S.We made complex immunehistology ex amination of local immune system of segmental bronchus for 54 patients with chronic obstructive pulmonary disease. In the article author give principles about allocation and quantitative index for immunocompetent cells. We ascert ained correlation between level of expression, stage and clinic al course of disease. Our examination demonstrated ambiguous fate for local immunity cells duri ng formation of pathogenetical aspects about chronic obstructive pulmonary disease progress. There is a pronounced disbalance of immunoregulatory index. The predominance of cytotoxic lymphocytes is observed in the foci of disregeneration processes, namely, in proliferation, hyperpla-sia, squamous metaplasia and dysp lasia of the bronchial epithelium.http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12mlsozl.pdfchronic obstructive pulmonary diseaseimmunocompetent cellssegmental bronchus |
spellingShingle | Malofiy L.S. Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease Морфологія chronic obstructive pulmonary disease immunocompetent cells segmental bronchus |
title | Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease |
title_full | Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease |
title_fullStr | Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease |
title_full_unstemmed | Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease |
title_short | Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease |
title_sort | peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob structive pulmonary disease |
topic | chronic obstructive pulmonary disease immunocompetent cells segmental bronchus |
url | http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12mlsozl.pdf |
work_keys_str_mv | AT malofiyls peculiarityofimmunocompetentcellsallocationinsegmentalbronchusforpatientswithchronicobstructivepulmonarydisease |