Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease

We made complex immunehistology ex amination of local immune system of segmental bronchus for 54 patients with chronic obstructive pulmonary disease. In the article author give principles about allocation and quantitative index for immunocompetent cells. We ascert ained correlation between level of...

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Main Author: Malofiy L.S.
Format: Article
Language:Russian
Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2012-01-01
Series:Морфологія
Subjects:
Online Access:http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12mlsozl.pdf
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author Malofiy L.S.
author_facet Malofiy L.S.
author_sort Malofiy L.S.
collection DOAJ
description We made complex immunehistology ex amination of local immune system of segmental bronchus for 54 patients with chronic obstructive pulmonary disease. In the article author give principles about allocation and quantitative index for immunocompetent cells. We ascert ained correlation between level of expression, stage and clinic al course of disease. Our examination demonstrated ambiguous fate for local immunity cells duri ng formation of pathogenetical aspects about chronic obstructive pulmonary disease progress. There is a pronounced disbalance of immunoregulatory index. The predominance of cytotoxic lymphocytes is observed in the foci of disregeneration processes, namely, in proliferation, hyperpla-sia, squamous metaplasia and dysp lasia of the bronchial epithelium.
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spelling doaj.art-e1c4a967619f4a7ca3e389d9e86a60732022-12-22T01:49:49ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96652012-01-01613742Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary diseaseMalofiy L.S.We made complex immunehistology ex amination of local immune system of segmental bronchus for 54 patients with chronic obstructive pulmonary disease. In the article author give principles about allocation and quantitative index for immunocompetent cells. We ascert ained correlation between level of expression, stage and clinic al course of disease. Our examination demonstrated ambiguous fate for local immunity cells duri ng formation of pathogenetical aspects about chronic obstructive pulmonary disease progress. There is a pronounced disbalance of immunoregulatory index. The predominance of cytotoxic lymphocytes is observed in the foci of disregeneration processes, namely, in proliferation, hyperpla-sia, squamous metaplasia and dysp lasia of the bronchial epithelium.http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12mlsozl.pdfchronic obstructive pulmonary diseaseimmunocompetent cellssegmental bronchus
spellingShingle Malofiy L.S.
Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
Морфологія
chronic obstructive pulmonary disease
immunocompetent cells
segmental bronchus
title Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
title_full Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
title_fullStr Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
title_full_unstemmed Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
title_short Peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob-structive pulmonary disease
title_sort peculiarity of immunocompetent cells allocation in segmental bronchus for patients with chronic ob structive pulmonary disease
topic chronic obstructive pulmonary disease
immunocompetent cells
segmental bronchus
url http://www.morphology.dp.ua/_pub/MORPHO-2012-06-01/12mlsozl.pdf
work_keys_str_mv AT malofiyls peculiarityofimmunocompetentcellsallocationinsegmentalbronchusforpatientswithchronicobstructivepulmonarydisease