Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data
Abstract Background Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer’s disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to...
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | Alzheimer’s Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13195-022-01056-x |
| _version_ | 1797806876015984640 |
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| author | Francesca Conca Valentina Esposito Francesco Rundo Davide Quaranta Cristina Muscio Rosa Manenti Giulia Caruso Ugo Lucca Alessia Antonella Galbussera Sonia Di Tella Francesca Baglio Federica L’Abbate Elisa Canu Valentina Catania Massimo Filippi Giulia Mattavelli Barbara Poletti Vincenzo Silani Raffaele Lodi Maddalena De Matteis Michelangelo Stanzani Maserati Andrea Arighi Emanuela Rotondo Antonio Tanzilli Andrea Pace Federica Garramone Carlo Cavaliere Matteo Pardini Cristiano Rizzetto Sandro Sorbi Roberta Perri Pietro Tiraboschi Nicola Canessa Maria Cotelli Raffaele Ferri Sandra Weintraub Camillo Marra Fabrizio Tagliavini Eleonora Catricalà Stefano Francesco Cappa |
| author_facet | Francesca Conca Valentina Esposito Francesco Rundo Davide Quaranta Cristina Muscio Rosa Manenti Giulia Caruso Ugo Lucca Alessia Antonella Galbussera Sonia Di Tella Francesca Baglio Federica L’Abbate Elisa Canu Valentina Catania Massimo Filippi Giulia Mattavelli Barbara Poletti Vincenzo Silani Raffaele Lodi Maddalena De Matteis Michelangelo Stanzani Maserati Andrea Arighi Emanuela Rotondo Antonio Tanzilli Andrea Pace Federica Garramone Carlo Cavaliere Matteo Pardini Cristiano Rizzetto Sandro Sorbi Roberta Perri Pietro Tiraboschi Nicola Canessa Maria Cotelli Raffaele Ferri Sandra Weintraub Camillo Marra Fabrizio Tagliavini Eleonora Catricalà Stefano Francesco Cappa |
| author_sort | Francesca Conca |
| collection | DOAJ |
| description | Abstract Background Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer’s disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to solve this issue. Methods Following the initiative of the University of Washington’s National Alzheimer’s Coordinating Center (NACC), we presented the Italian adaptation of the Neuropsychological Test Battery of the Uniform Data Set (I-UDSNB). We collected data from 433 healthy Italian individuals and employed regression models to evaluate the impact of demographic variables on the performance, deriving the reference norms. Results Higher education and lower age were associated with a better performance in the majority of tests, while sex affected only fluency tests and Digit Span Forward. Conclusions The I-UDSNB offers a valuable and harmonized tool for neuropsychological testing in Italy, to be used in clinical and research settings. |
| first_indexed | 2024-03-13T06:14:01Z |
| format | Article |
| id | doaj.art-e1c77339d8c34b469548ba2aa3ae9bb6 |
| institution | Directory Open Access Journal |
| issn | 1758-9193 |
| language | English |
| last_indexed | 2024-03-13T06:14:01Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Alzheimer’s Research & Therapy |
| spelling | doaj.art-e1c77339d8c34b469548ba2aa3ae9bb62023-06-11T11:07:35ZengBMCAlzheimer’s Research & Therapy1758-91932022-08-0114111110.1186/s13195-022-01056-xItalian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative dataFrancesca Conca0Valentina Esposito1Francesco Rundo2Davide Quaranta3Cristina Muscio4Rosa Manenti5Giulia Caruso6Ugo Lucca7Alessia Antonella Galbussera8Sonia Di Tella9Francesca Baglio10Federica L’Abbate11Elisa Canu12Valentina Catania13Massimo Filippi14Giulia Mattavelli15Barbara Poletti16Vincenzo Silani17Raffaele Lodi18Maddalena De Matteis19Michelangelo Stanzani Maserati20Andrea Arighi21Emanuela Rotondo22Antonio Tanzilli23Andrea Pace24Federica Garramone25Carlo Cavaliere26Matteo Pardini27Cristiano Rizzetto28Sandro Sorbi29Roberta Perri30Pietro Tiraboschi31Nicola Canessa32Maria Cotelli33Raffaele Ferri34Sandra Weintraub35Camillo Marra36Fabrizio Tagliavini37Eleonora Catricalà38Stefano Francesco Cappa39IRCCS Mondino FoundationIRCCS Mondino FoundationDepartment of Neurology IC, Oasi Research Institute – IRCCSNeurology Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCSFondazione IRCCS Istituto Neurologico Carlo BestaIRCCS Istituto Centro San Giovanni di Dio FatebenefratelliLaboratory of Clinical and Behavioural Neurology, IRCCS Santa Lucia FoundationLaboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCSLaboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCSIRCCS Fondazione Don Carlo Gnocchi, ONLUSIRCCS Fondazione Don Carlo Gnocchi, ONLUSNeurology Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCSNeuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific InstituteUnit of Psychology I.C., Oasi Research Institute–IRCCSNeuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific InstituteIUSS Cognitive Neuroscience (ICON) Center, Scuola Universitaria Superiore IUSSDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico ItalianoDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico ItalianoIRCCS Istituto delle Scienze Neurologiche di BolognaIRCCS Istituto delle Scienze Neurologiche di BolognaIRCCS Istituto delle Scienze Neurologiche di BolognaFondazione IRCSS ca’ Granda, Ospedale PoliclinicoFondazione IRCSS ca’ Granda, Ospedale PoliclinicoNeuro-Oncology Unit, IRCCS Regina Elena National Cancer InstituteNeuro-Oncology Unit, IRCCS Regina Elena National Cancer InstituteIRCCS Synlab SDN of NaplesIRCCS Synlab SDN of NaplesIRCCS Ospedale Policlinico San MartinoIRCCS Ospedale Policlinico San MartinoIRCCS Fondazione Don Carlo Gnocchi, ONLUSLaboratory of Clinical and Behavioural Neurology, IRCCS Santa Lucia FoundationFondazione IRCCS Istituto Neurologico Carlo BestaIUSS Cognitive Neuroscience (ICON) Center, Scuola Universitaria Superiore IUSSIRCCS Istituto Centro San Giovanni di Dio FatebenefratelliDepartment of Neurology IC, Oasi Research Institute – IRCCSMesulam Center for Cognitive Neurology and Alzheimer’s Disease and Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Department of Neurology, Northwestern UniversityNeurology Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCSFondazione IRCCS Istituto Neurologico Carlo BestaIRCCS Mondino FoundationIRCCS Mondino FoundationAbstract Background Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer’s disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to solve this issue. Methods Following the initiative of the University of Washington’s National Alzheimer’s Coordinating Center (NACC), we presented the Italian adaptation of the Neuropsychological Test Battery of the Uniform Data Set (I-UDSNB). We collected data from 433 healthy Italian individuals and employed regression models to evaluate the impact of demographic variables on the performance, deriving the reference norms. Results Higher education and lower age were associated with a better performance in the majority of tests, while sex affected only fluency tests and Digit Span Forward. Conclusions The I-UDSNB offers a valuable and harmonized tool for neuropsychological testing in Italy, to be used in clinical and research settings.https://doi.org/10.1186/s13195-022-01056-xNeuropsychological testsUDSAlzheimer’s diseaseCognition |
| spellingShingle | Francesca Conca Valentina Esposito Francesco Rundo Davide Quaranta Cristina Muscio Rosa Manenti Giulia Caruso Ugo Lucca Alessia Antonella Galbussera Sonia Di Tella Francesca Baglio Federica L’Abbate Elisa Canu Valentina Catania Massimo Filippi Giulia Mattavelli Barbara Poletti Vincenzo Silani Raffaele Lodi Maddalena De Matteis Michelangelo Stanzani Maserati Andrea Arighi Emanuela Rotondo Antonio Tanzilli Andrea Pace Federica Garramone Carlo Cavaliere Matteo Pardini Cristiano Rizzetto Sandro Sorbi Roberta Perri Pietro Tiraboschi Nicola Canessa Maria Cotelli Raffaele Ferri Sandra Weintraub Camillo Marra Fabrizio Tagliavini Eleonora Catricalà Stefano Francesco Cappa Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data Alzheimer’s Research & Therapy Neuropsychological tests UDS Alzheimer’s disease Cognition |
| title | Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data |
| title_full | Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data |
| title_fullStr | Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data |
| title_full_unstemmed | Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data |
| title_short | Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data |
| title_sort | italian adaptation of the uniform data set neuropsychological test battery i udsnb 1 0 development and normative data |
| topic | Neuropsychological tests UDS Alzheimer’s disease Cognition |
| url | https://doi.org/10.1186/s13195-022-01056-x |
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