Modern Radiotherapy and Cardiac Toxicity in Breast Cancer
Radiotherapy (RT) is a mainstay of Breast Cancer (BC) patients therapy. Nonetheless, unintended irradiation of the heart and its substructures can result in cardiac toxicity, jeopardizing long-term survivors’ quality of life (QOL). Advances in RT delivery techniques deeply impacted this clinical sce...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2023-07-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/50/7/10.31083/j.ceog5007138 |
| _version_ | 1797768998898630656 |
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| author | Giuseppe Carlo Iorio Valeria Chiofalo Umberto Ricardi |
| author_facet | Giuseppe Carlo Iorio Valeria Chiofalo Umberto Ricardi |
| author_sort | Giuseppe Carlo Iorio |
| collection | DOAJ |
| description | Radiotherapy (RT) is a mainstay of Breast Cancer (BC) patients therapy. Nonetheless, unintended irradiation of the heart and its substructures can result in cardiac toxicity, jeopardizing long-term survivors’ quality of life (QOL). Advances in RT delivery techniques deeply impacted this clinical scenario. Indeed, given the non-negligible burden of cardiotoxicity, modern cardiac sparing approaches have a pivotal role. Nonetheless, further evidence is eagerly awaited regarding patients’ selection, clinical predictors, biological markers, and particularly heart substructures dose-constraints. |
| first_indexed | 2024-03-12T21:02:27Z |
| format | Article |
| id | doaj.art-e1ceae0a848c4f55857800c6c4c87903 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-03-12T21:02:27Z |
| publishDate | 2023-07-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-e1ceae0a848c4f55857800c6c4c879032023-07-31T06:06:12ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632023-07-0150713810.31083/j.ceog5007138S0390-6663(23)02079-1Modern Radiotherapy and Cardiac Toxicity in Breast CancerGiuseppe Carlo Iorio0Valeria Chiofalo1Umberto Ricardi2Department of Oncology, University of Torino, 10125 Torino, ItalyDepartment of Oncology, University of Torino, 10125 Torino, ItalyDepartment of Oncology, University of Torino, 10125 Torino, ItalyRadiotherapy (RT) is a mainstay of Breast Cancer (BC) patients therapy. Nonetheless, unintended irradiation of the heart and its substructures can result in cardiac toxicity, jeopardizing long-term survivors’ quality of life (QOL). Advances in RT delivery techniques deeply impacted this clinical scenario. Indeed, given the non-negligible burden of cardiotoxicity, modern cardiac sparing approaches have a pivotal role. Nonetheless, further evidence is eagerly awaited regarding patients’ selection, clinical predictors, biological markers, and particularly heart substructures dose-constraints.https://www.imrpress.com/journal/CEOG/50/7/10.31083/j.ceog5007138breast cancerradiotherapycardiac toxicitydibhqolcardiac sparing |
| spellingShingle | Giuseppe Carlo Iorio Valeria Chiofalo Umberto Ricardi Modern Radiotherapy and Cardiac Toxicity in Breast Cancer Clinical and Experimental Obstetrics & Gynecology breast cancer radiotherapy cardiac toxicity dibh qol cardiac sparing |
| title | Modern Radiotherapy and Cardiac Toxicity in Breast Cancer |
| title_full | Modern Radiotherapy and Cardiac Toxicity in Breast Cancer |
| title_fullStr | Modern Radiotherapy and Cardiac Toxicity in Breast Cancer |
| title_full_unstemmed | Modern Radiotherapy and Cardiac Toxicity in Breast Cancer |
| title_short | Modern Radiotherapy and Cardiac Toxicity in Breast Cancer |
| title_sort | modern radiotherapy and cardiac toxicity in breast cancer |
| topic | breast cancer radiotherapy cardiac toxicity dibh qol cardiac sparing |
| url | https://www.imrpress.com/journal/CEOG/50/7/10.31083/j.ceog5007138 |
| work_keys_str_mv | AT giuseppecarloiorio modernradiotherapyandcardiactoxicityinbreastcancer AT valeriachiofalo modernradiotherapyandcardiactoxicityinbreastcancer AT umbertoricardi modernradiotherapyandcardiactoxicityinbreastcancer |