Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir

Abstract COVID‐19 in cancer patients on immunosuppressive agents for the treatment of immune‐related adverse events of immune checkpoint inhibitors can rapidly deteriorate. The combination therapy with methylprednisolone, baricitinib, and remdesivir may be effective for critical COVID‐19, and furthe...

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Main Authors: Naohiro Oda, Keiji Miyoshi, Daisuke Morichika, Yuka Beika, Takahiro Taki, Reo Mitani, Toshiaki Okada, Ichiro Takata
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.4459
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author Naohiro Oda
Keiji Miyoshi
Daisuke Morichika
Yuka Beika
Takahiro Taki
Reo Mitani
Toshiaki Okada
Ichiro Takata
author_facet Naohiro Oda
Keiji Miyoshi
Daisuke Morichika
Yuka Beika
Takahiro Taki
Reo Mitani
Toshiaki Okada
Ichiro Takata
author_sort Naohiro Oda
collection DOAJ
description Abstract COVID‐19 in cancer patients on immunosuppressive agents for the treatment of immune‐related adverse events of immune checkpoint inhibitors can rapidly deteriorate. The combination therapy with methylprednisolone, baricitinib, and remdesivir may be effective for critical COVID‐19, and further clinical trials are warranted.
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spelling doaj.art-e1cf2529d28f48dfb3f0dab67d7fb3662023-03-27T08:34:50ZengWileyClinical Case Reports2050-09042021-07-0197n/an/a10.1002/ccr3.4459Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivirNaohiro Oda0Keiji Miyoshi1Daisuke Morichika2Yuka Beika3Takahiro Taki4Reo Mitani5Toshiaki Okada6Ichiro Takata7Department of Internal Medicine Fukuyama City Hospital Fukuyama JapanDepartment of Respiratory Medicine Fukuyama Medical Center Fukuyama JapanDepartment of Respiratory Medicine Fukuyama Medical Center Fukuyama JapanDepartment of Respiratory Medicine Fukuyama Medical Center Fukuyama JapanDepartment of Internal Medicine Fukuyama City Hospital Fukuyama JapanDepartment of Internal Medicine Fukuyama City Hospital Fukuyama JapanDepartment of Respiratory Medicine Fukuyama Medical Center Fukuyama JapanDepartment of Internal Medicine Fukuyama City Hospital Fukuyama JapanAbstract COVID‐19 in cancer patients on immunosuppressive agents for the treatment of immune‐related adverse events of immune checkpoint inhibitors can rapidly deteriorate. The combination therapy with methylprednisolone, baricitinib, and remdesivir may be effective for critical COVID‐19, and further clinical trials are warranted.https://doi.org/10.1002/ccr3.4459baricitinibCOVID‐19immune checkpoint inhibitorimmune‐related adverse eventlung cancer
spellingShingle Naohiro Oda
Keiji Miyoshi
Daisuke Morichika
Yuka Beika
Takahiro Taki
Reo Mitani
Toshiaki Okada
Ichiro Takata
Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir
Clinical Case Reports
baricitinib
COVID‐19
immune checkpoint inhibitor
immune‐related adverse event
lung cancer
title Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir
title_full Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir
title_fullStr Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir
title_full_unstemmed Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir
title_short Successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab‐induced arthritis by methylprednisolone, baricitinib, and remdesivir
title_sort successful treatment of critical coronavirus disease 2019 in a patient with lung cancer concomitant with pembrolizumab induced arthritis by methylprednisolone baricitinib and remdesivir
topic baricitinib
COVID‐19
immune checkpoint inhibitor
immune‐related adverse event
lung cancer
url https://doi.org/10.1002/ccr3.4459
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