L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson’s Disease Models

L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson’s Disease Models

The altered crosstalk between mitochondrial dysfunction, intracellular Ca<sup>2+</sup> homeostasis, and oxidative stress has a central role in the dopaminergic neurodegeneration. In the present study, we investigated the hypothesis that pharmacological strategies able to improve mitochon...

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Bibliographic Details
Main Authors:	Maria Josè Sisalli, Salvatore Della Notte, Agnese Secondo, Carmelo Ventra, Lucio Annunziato, Antonella Scorziello
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Series:	Cells
Subjects:	mitochondria calcium homeostasis ornithine NO sodium-calcium-exchangers Parkinson’s disease
Online Access:	https://www.mdpi.com/2073-4409/11/18/2909

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