Development and verification of a combined immune- and cancer-associated fibroblast related prognostic signature for colon adenocarcinoma

Development and verification of a combined immune- and cancer-associated fibroblast related prognostic signature for colon adenocarcinoma

IntroductionTo better understand the role of immune escape and cancer-associated fibroblasts (CAFs) in colon adenocarcinoma (COAD), an integrative analysis of the tumor microenvironment was performed using a set of 12 immune- and CAF-related genes (ICRGs).MethodsUnivariate and least absolute shrinka...

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Bibliographic Details
Main Authors: Jingsun Wei, Xiaoxu Ge, Yucheng Qian, Kai Jiang, Xin Chen, Wei Lu, Hang Yang, Dongliang Fu, Yimin Fang, Xinyi Zhou, Qian Xiao, Yang Tang, Kefeng Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
immune
CAF
prognosis
colon adenocarcinoma
TME
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1291938/full

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