The phytochemical and pharmacological actions of Entada africana Guill. & Perr.

Entada africana (Ea, Asteraceae) has been widely used traditionally to treat different ailments, as food, insecticides, source of gums, in some small carpentry works. Studies on the pharmacognostic characterization, nutritional, elemental and physicochemical contents has been reported. In vivo and i...

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Main Authors: A.J. Yusuf, M.I. Abdullahi
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019359924
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author A.J. Yusuf
M.I. Abdullahi
author_facet A.J. Yusuf
M.I. Abdullahi
author_sort A.J. Yusuf
collection DOAJ
description Entada africana (Ea, Asteraceae) has been widely used traditionally to treat different ailments, as food, insecticides, source of gums, in some small carpentry works. Studies on the pharmacognostic characterization, nutritional, elemental and physicochemical contents has been reported. In vivo and in vitro studies on the plant validated some ethnomedicinal claims of the use of the plant as an anti-inflammatory, analgesic, antibacterial, antioxidant, antiviral, anti-angiogenic, cytotoxic agents among others. Triterpenes, saponins, flavonoids and sugars were reported as bioactive constituents which might be responsible for the aforementioned pharmacological actions of the plant.However, more researches are required in order to isolate bioactive compounds from the different parts of Ea and evaluate their effects on different ailments.
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spelling doaj.art-e1d42d30e916411c94926f77805ae0b02022-12-21T23:52:48ZengElsevierHeliyon2405-84402019-09-0159e02332The phytochemical and pharmacological actions of Entada africana Guill. & Perr.A.J. Yusuf0M.I. Abdullahi1Corresponding author.; Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto, NigeriaDepartment of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto, NigeriaEntada africana (Ea, Asteraceae) has been widely used traditionally to treat different ailments, as food, insecticides, source of gums, in some small carpentry works. Studies on the pharmacognostic characterization, nutritional, elemental and physicochemical contents has been reported. In vivo and in vitro studies on the plant validated some ethnomedicinal claims of the use of the plant as an anti-inflammatory, analgesic, antibacterial, antioxidant, antiviral, anti-angiogenic, cytotoxic agents among others. Triterpenes, saponins, flavonoids and sugars were reported as bioactive constituents which might be responsible for the aforementioned pharmacological actions of the plant.However, more researches are required in order to isolate bioactive compounds from the different parts of Ea and evaluate their effects on different ailments.http://www.sciencedirect.com/science/article/pii/S2405844019359924Natural product chemistryAntioxidantAnti-angiogenicTriterpenesAnti-inflammatoryAntibacterial
spellingShingle A.J. Yusuf
M.I. Abdullahi
The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
Heliyon
Natural product chemistry
Antioxidant
Anti-angiogenic
Triterpenes
Anti-inflammatory
Antibacterial
title The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
title_full The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
title_fullStr The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
title_full_unstemmed The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
title_short The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
title_sort phytochemical and pharmacological actions of entada africana guill amp perr
topic Natural product chemistry
Antioxidant
Anti-angiogenic
Triterpenes
Anti-inflammatory
Antibacterial
url http://www.sciencedirect.com/science/article/pii/S2405844019359924
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