Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance
ABSTRACTBacterial biofilms have attracted significant attention due to their involvement in persistent infections, food and water contamination, and infrastructure corrosion. This review delves into the intricate interactions between bacterial biofilms and unicellular parasites, shedding light on th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
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| Series: | Virulence |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21505594.2023.2289775 |
| _version_ | 1797401652850851840 |
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| author | Eva Zanditenas Serge Ankri |
| author_facet | Eva Zanditenas Serge Ankri |
| author_sort | Eva Zanditenas |
| collection | DOAJ |
| description | ABSTRACTBacterial biofilms have attracted significant attention due to their involvement in persistent infections, food and water contamination, and infrastructure corrosion. This review delves into the intricate interactions between bacterial biofilms and unicellular parasites, shedding light on their impact on biofilm formation, structure, and function. Unicellular parasites, including protozoa, influence bacterial biofilms through grazing activities, leading to adaptive changes in bacterial communities. Moreover, parasites like Leishmania and Giardia can shape biofilm composition in a grazing independent manner, potentially influencing disease outcomes. Biofilms, acting as reservoirs, enable the survival of protozoan parasites against environmental stressors and antimicrobial agents. Furthermore, these biofilms may influence parasite virulence and stress responses, posing challenges in disease treatment. Interactions between unicellular parasites and fungal-containing biofilms is also discussed, hinting at complex microbial relationships in various ecosystems. Understanding these interactions offers insights into disease mechanisms and antibiotic resistance dissemination, paving the way for innovative therapeutic strategies and ecosystem-level implications. |
| first_indexed | 2024-03-09T02:13:11Z |
| format | Article |
| id | doaj.art-e1d4d29a87914303905b84d8281d8359 |
| institution | Directory Open Access Journal |
| issn | 2150-5594 2150-5608 |
| language | English |
| last_indexed | 2024-03-09T02:13:11Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Virulence |
| spelling | doaj.art-e1d4d29a87914303905b84d8281d83592023-12-07T05:32:27ZengTaylor & Francis GroupVirulence2150-55942150-56082024-12-0115110.1080/21505594.2023.2289775Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistanceEva Zanditenas0Serge Ankri1Department of Molecular Microbiology, Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, IsraelDepartment of Molecular Microbiology, Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, IsraelABSTRACTBacterial biofilms have attracted significant attention due to their involvement in persistent infections, food and water contamination, and infrastructure corrosion. This review delves into the intricate interactions between bacterial biofilms and unicellular parasites, shedding light on their impact on biofilm formation, structure, and function. Unicellular parasites, including protozoa, influence bacterial biofilms through grazing activities, leading to adaptive changes in bacterial communities. Moreover, parasites like Leishmania and Giardia can shape biofilm composition in a grazing independent manner, potentially influencing disease outcomes. Biofilms, acting as reservoirs, enable the survival of protozoan parasites against environmental stressors and antimicrobial agents. Furthermore, these biofilms may influence parasite virulence and stress responses, posing challenges in disease treatment. Interactions between unicellular parasites and fungal-containing biofilms is also discussed, hinting at complex microbial relationships in various ecosystems. Understanding these interactions offers insights into disease mechanisms and antibiotic resistance dissemination, paving the way for innovative therapeutic strategies and ecosystem-level implications.https://www.tandfonline.com/doi/10.1080/21505594.2023.2289775Bacterial biofilmsunicellular parasiteextracellular polymeric substances (EPS)nutrientsbiofilm componentsbiofilm degradation |
| spellingShingle | Eva Zanditenas Serge Ankri Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance Virulence Bacterial biofilms unicellular parasite extracellular polymeric substances (EPS) nutrients biofilm components biofilm degradation |
| title | Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance |
| title_full | Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance |
| title_fullStr | Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance |
| title_full_unstemmed | Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance |
| title_short | Unraveling the interplay between unicellular parasites and bacterial biofilms: Implications for disease persistence and antibiotic resistance |
| title_sort | unraveling the interplay between unicellular parasites and bacterial biofilms implications for disease persistence and antibiotic resistance |
| topic | Bacterial biofilms unicellular parasite extracellular polymeric substances (EPS) nutrients biofilm components biofilm degradation |
| url | https://www.tandfonline.com/doi/10.1080/21505594.2023.2289775 |
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