The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery
The aim of this study was to investigate the impact of liver cirrhosis (LC) on postoperative complications and long-term outcomes in patients who underwent cardiac surgery. Three databases, including PubMed, Embase, and the Cochrane Library, were searched on July 24, 2022. A total of 1,535,129 patie...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Ubiquity Press
2023-10-01
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| Series: | Global Heart |
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| Online Access: | https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1270 |
| _version_ | 1827672316672212992 |
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| author | Fei Liu Zi-Wei Li Xu-Rui Liu Xiao-Yu Liu Jun Yang |
| author_facet | Fei Liu Zi-Wei Li Xu-Rui Liu Xiao-Yu Liu Jun Yang |
| author_sort | Fei Liu |
| collection | DOAJ |
| description | The aim of this study was to investigate the impact of liver cirrhosis (LC) on postoperative complications and long-term outcomes in patients who underwent cardiac surgery. Three databases, including PubMed, Embase, and the Cochrane Library, were searched on July 24, 2022. A total of 1,535,129 patients were enrolled in the seven included studies for analysis. According to our analysis, LC was a risk factor for postoperative overall complications (OR = 1.48, 95% CI = 1.21 to 1.81, I2 = 90.35%, P = 0.00 < 0.1). For various complications, more patients developed pulmonary (OR = 1.86, 95% CI = 1.21 to 2.87, I2 = 90.79%, P = 0.00 < 0.1), gastrointestinal (OR = 2.03, 95% CI = 1.32 to 3.11, I2 = 0.00%, P = 0.00 < 0.05), renal (OR = 2.20, 95% CI = 1.41 to 3.45, I2 = 91.60%, P = 0.00 < 0.1), neurological (OR = 1.14, 95% CI = 1.03 to 1.26, I2 = 7.35%, P = 0.01 < 0.05), and infectious (OR = 2.02, 95% CI = 1.17 to 3.50, I2 = 92.37%, P = 0.01 < 0.1) complications after surgery in the LC group. As for cardiovascular (OR = 1.07, 95% CI = 0.85 to 1.35, I2 = 75.23%, P = 0.58 > 0.1) complications, there was no statistical significance between the 2 groups. As for long-term outcomes, we found that in-hospital death (OR = 2.53, 95% CI = 1.86 to 3.20, I2 = 44.58%, P = 0.00 < 0.05) and death (OR = 3.31, 95% CI = 1.54 to 5.07, I2 = 93.81%, P = 0.00 < 0.1) in the LC group were higher than the non-LC group. LC was a risk factor for cardiac surgery. Patients with LC who would undergo cardiac surgery should be fully assessed for the risks of cardiac surgery. Similarly, the surgeon should assess the patient’s liver function before surgery. |
| first_indexed | 2024-03-10T04:02:52Z |
| format | Article |
| id | doaj.art-e1d654381d7c43f3b2d4a316dc3470f3 |
| institution | Directory Open Access Journal |
| issn | 2211-8179 |
| language | English |
| last_indexed | 2024-03-10T04:02:52Z |
| publishDate | 2023-10-01 |
| publisher | Ubiquity Press |
| record_format | Article |
| series | Global Heart |
| spelling | doaj.art-e1d654381d7c43f3b2d4a316dc3470f32023-11-23T08:31:37ZengUbiquity PressGlobal Heart2211-81792023-10-01181545410.5334/gh.12701251The Effect of Liver Cirrhosis on Patients Undergoing Cardiac SurgeryFei Liu0https://orcid.org/0000-0002-4022-0732Zi-Wei Li1https://orcid.org/0000-0001-9759-4535Xu-Rui Liu2https://orcid.org/0000-0002-6069-2104Xiao-Yu Liu3https://orcid.org/0000-0001-9448-4592Jun Yang4https://orcid.org/0000-0003-2794-7360Department of Gastrointestinal Surgery, the First Affiliated Hospital of Chongqing Medical University, ChongqingDepartment of Gastrointestinal Surgery, the First Affiliated Hospital of Chongqing Medical University, ChongqingDepartment of Gastrointestinal Surgery, the First Affiliated Hospital of Chongqing Medical University, ChongqingDepartment of Gastrointestinal Surgery, the First Affiliated Hospital of Chongqing Medical University, ChongqingDepartment of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, ChongqingThe aim of this study was to investigate the impact of liver cirrhosis (LC) on postoperative complications and long-term outcomes in patients who underwent cardiac surgery. Three databases, including PubMed, Embase, and the Cochrane Library, were searched on July 24, 2022. A total of 1,535,129 patients were enrolled in the seven included studies for analysis. According to our analysis, LC was a risk factor for postoperative overall complications (OR = 1.48, 95% CI = 1.21 to 1.81, I2 = 90.35%, P = 0.00 < 0.1). For various complications, more patients developed pulmonary (OR = 1.86, 95% CI = 1.21 to 2.87, I2 = 90.79%, P = 0.00 < 0.1), gastrointestinal (OR = 2.03, 95% CI = 1.32 to 3.11, I2 = 0.00%, P = 0.00 < 0.05), renal (OR = 2.20, 95% CI = 1.41 to 3.45, I2 = 91.60%, P = 0.00 < 0.1), neurological (OR = 1.14, 95% CI = 1.03 to 1.26, I2 = 7.35%, P = 0.01 < 0.05), and infectious (OR = 2.02, 95% CI = 1.17 to 3.50, I2 = 92.37%, P = 0.01 < 0.1) complications after surgery in the LC group. As for cardiovascular (OR = 1.07, 95% CI = 0.85 to 1.35, I2 = 75.23%, P = 0.58 > 0.1) complications, there was no statistical significance between the 2 groups. As for long-term outcomes, we found that in-hospital death (OR = 2.53, 95% CI = 1.86 to 3.20, I2 = 44.58%, P = 0.00 < 0.05) and death (OR = 3.31, 95% CI = 1.54 to 5.07, I2 = 93.81%, P = 0.00 < 0.1) in the LC group were higher than the non-LC group. LC was a risk factor for cardiac surgery. Patients with LC who would undergo cardiac surgery should be fully assessed for the risks of cardiac surgery. Similarly, the surgeon should assess the patient’s liver function before surgery.https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1270liver cirrhosiscardiac surgerycomplications |
| spellingShingle | Fei Liu Zi-Wei Li Xu-Rui Liu Xiao-Yu Liu Jun Yang The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery Global Heart liver cirrhosis cardiac surgery complications |
| title | The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery |
| title_full | The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery |
| title_fullStr | The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery |
| title_full_unstemmed | The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery |
| title_short | The Effect of Liver Cirrhosis on Patients Undergoing Cardiac Surgery |
| title_sort | effect of liver cirrhosis on patients undergoing cardiac surgery |
| topic | liver cirrhosis cardiac surgery complications |
| url | https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1270 |
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