The pharmacokinetics of midazolam and 1-OH-midazolam during oral premedication in paediatric patients

The pharmacokinetics of midazolam and 1-OH-midazolam during oral premedication in paediatric patients

Objective. Development of midazolam (MDZ) pharmacokinetic model is pivotal for predicting drug response and determining appropriate dosing in patients who undergo surgical procedures. The aim of this study was to provide population pharmacokinetic analysis describing MDZ and its main metabolite 1-OH...

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Bibliographic Details
Main Authors: Alicja Bartkowska-Śniatkowska, Pawel Wiczling, Magdalena Juzwa-Sobieraj, Ewelina Kałużna, Bogna Świątek-Kościelna, Agnieszka Bienert, Agnieszka Borsuk, Artur Tezyk, Jowita Rosada-Kurasinska, Danuta Januszkiewicz-Lewandowska
Format: Article
Language:English
Published: Poznan University of Medical Sciences 2016-06-01
Series:Journal of Medical Science
Subjects:
midazolam
midazolam pharmacokinetic model
1-OH-midazolam
Online Access:https://jms.ump.edu.pl/index.php/JMS/article/view/112

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