In vitro and in vivo evaluation of antifungal combinations against azole-resistant Aspergillus fumigatus isolates

In vitro and in vivo evaluation of antifungal combinations against azole-resistant Aspergillus fumigatus isolates

Azole resistance in Aspergillus fumigatus (Af) has become a widespread threat and a major concern for optimal management of patients with invasive aspergillosis (IA). Combination of echinocandins with azoles is an attractive alternative option for the treatment of IA due to azole-resistant Af strain...

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Bibliographic Details
Main Authors: Sana Jemel, Yannick Raveloarisaona, Anne-Laure Bidaud, Elie Djenontin, Aicha Kallel, Jacques Guillot, Kalthoum Kallel, Françoise Botterel, Eric Dannaoui
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Aspergillus fumigatus (A. fumigatus)
antifungal combination
Galleria mellonella
voriconazole
posaconazole
caspofungin
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1038342/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1038342/full

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